Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 Biomarker disease BEFREE Impact of CYP2D6 on venlafaxine metabolism in Trinidadian patients with major depressive disorder. 29327975 2018
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 GeneticVariation disease BEFREE Influence of the cytochrome P450 2D6 *10/*10 genotype on the pharmacokinetics of paroxetine in Japanese patients with major depressive disorder: a population pharmacokinetic analysis. 27187662 2016
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 Biomarker disease PSYGENET 47 patients with Major Depressive Disorder, treated with V 75 - 300 mg/day, underwent CYP2D6 genotyping using the INFINITI-CYP2D6 assay. 24660534 2014
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 GeneticVariation disease BEFREE A total of 149 inpatients with a diagnosis of major depressive disorder at the Institute of Living, Hartford Hospital (CT, USA), were genotyped to detect altered alleles in the CYP2D6 gene. 23734807 2013
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 Biomarker disease PSYGENET The impact of Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes on suicide attempt and suicide risk-a European multicentre study on treatment-resistant major depressive disorder. 23081704 2013
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 Biomarker disease PSYGENET A total of 149 inpatients with a diagnosis of major depressive disorder at the Institute of Living, Hartford Hospital (CT, USA), were genotyped to detect altered alleles in the CYP2D6 gene. 23734807 2013
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 GeneticVariation disease BEFREE The objective of this study is to investigate the influence of the 5-HTTLPR (serotonin transporter-linked promoter region), cytochrome P450 2C19, and cytochrome P450 2D6 polymorphisms on escitalopram (ESC) and venlafaxine (VEN) responses in major depressive disorder. 24014145 2013
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 GeneticVariation disease BEFREE The impact of Cytochrome P450 CYP1A2, CYP2C9, CYP2C19 and CYP2D6 genes on suicide attempt and suicide risk-a European multicentre study on treatment-resistant major depressive disorder. 23081704 2013
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 Biomarker disease PSYGENET The objective of this study is to investigate the influence of the 5-HTTLPR (serotonin transporter-linked promoter region), cytochrome P450 2C19, and cytochrome P450 2D6 polymorphisms on escitalopram (ESC) and venlafaxine (VEN) responses in major depressive disorder. 24014145 2013
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 GeneticVariation disease BEFREE CYP2C9, CYP2C19 and CYP2D6 genotypes and clinical data were obtained for 150 consecutive, consenting hospital admissions with a diagnosis of major depressive disorder and who were treated with psychotropic medications. 21861666 2011
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 Biomarker disease PSYGENET CYP2C9, CYP2C19 and CYP2D6 genotypes and clinical data were obtained for 150 consecutive, consenting hospital admissions with a diagnosis of major depressive disorder and who were treated with psychotropic medications. 21861666 2011
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 GeneticVariation disease BEFREE The risk of major depression in CYP2D6*4/*4 was not significantly different from extensive metabolizers (OR = 0.85; 95% CI: 0.36-2.00; p = 0.72). 19374513 2009
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6
0.380 GeneticVariation disease BEFREE This paper explores the link between CYP2D6 genotype and antidepressant-associated ADRs in outpatients being treated for major depression with either nortriptyline or fluoxetine. 14716707 2004