| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.550 | GeneticVariation | disease | BEFREE | Alterations of S100A10 (p11) level are also implicated in the etiology of major depressive disorder. | 30760886 | 2019 | ||||
|
0.550 | AlteredExpression | disease | BEFREE | P11 (S100A10), a member of the S100 family of proteins, is expressed widely throughout the body and is involved in major depressive disorder and antidepressant response. | 28137881 | 2017 | ||||
|
0.550 | Biomarker | disease | CTD_human | Antidepressant treatment is associated with epigenetic alterations in the promoter of P11 in a genetic model of depression. | 21682946 | 2012 | ||||
|
0.550 | Biomarker | disease | PSYGENET | P11 (S100A10) as a potential biomarker of psychiatric patients at risk of suicide. | 20863517 | 2011 | ||||
|
0.550 | Biomarker | disease | PSYGENET | The etiology of major depression remains unknown, but dysfunction of serotonergic signaling has long been implicated in the pathophysiology of this disorder. p11 is an S100 family member recently identified as a serotonin 1B [5-hydroxytryptamine 1B (5-HT(1B))] and serotonin 4 (5-HT(4)) receptor-binding protein. | 20962330 | 2010 | ||||
|
0.550 | AlteredExpression | disease | BEFREE | We examined the peripheral blood mononuclear cell (PBMC) P11 mRNA of patients with PTSD (n=13), major depressive disorder (MDD, n=16), bipolar disorder (BP, n=24), and schizophrenia (SCZ, n=12) or controls (n=14) using quantitative real-time PCR and the circulating levels of cortisol in blood plasma and saliva of PTSD using radioimmunoassay kit CORT-CT2. | 19380152 | 2009 | ||||
|
0.550 | GeneticVariation | disease | BEFREE | Association study of p11 gene with major depressive disorder, suicidal behaviors and treatment response. | 18838110 | 2008 | ||||
|
0.550 | GeneticVariation | disease | BEFREE | Investigating the role of p11 (S100A10) sequence variation in susceptibility to major depression. | 17510952 | 2007 |