Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 GeneticVariation disease BEFREE Furthermore, RNA-Seq-based transcriptomic analysis indicated that expression levels of four core repair factors, xeroderma pigmentosum (XP) complementation group A (XPA), XPC, XPG, and XPF-ERCC1, are progressively up-regulated during differentiation, but not those of replication protein A (RPA) and transcription factor IIH (TFIIH). 30808711 2019
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 GeneticVariation disease BEFREE We investigated the correlation between the response to chemotherapy in patients and excision repair cross-complimenta-ry group 1 gene (ERCC1) and xeroderma pigmentosum complemen-tation group F gene (XPF) polymorphisms and the effect of these polymorphisms on the clinical outcome of gastric cancer. 25222248 2014
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 Biomarker disease BEFREE Excision repair cross-complementation group 1 (ERCC1) and xeroderma pigmentosum-F (XPF) in the nucleotide excision repair pathway have been effectively repairing DNA damage induced by chemotherapeutic agents. 24370899 2014
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 Biomarker disease GENOMICS_ENGLAND Malfunction of nuclease ERCC1-XPF results in diverse clinical manifestations and causes Cockayne syndrome, xeroderma pigmentosum, and Fanconi anemia. 23623389 2013
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 Biomarker disease GENOMICS_ENGLAND First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure. 17273966 2007
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 GeneticVariation disease BEFREE We analyzed 13 polymorphisms in seven DNA repair genes belonging to different repair pathways [X-ray repair cross-complementing group 1 (XRCC1): 26304C>T, 26651A>G, 28152A>G; xeroderma pigmentosum-D (XPD): 23591A>G, 35931A>C; excision repair complementing defective in Chinese hamster, group 1 (ERCC1): 19007C>T; XRCC3: 4541T>C, 17893A>G, 18067C>T; proliferating cell nuclear antigen (PCNA): 6084G>C; ERCC4: 30028C>T, 30147A>G; and XRCC2-31479A>G] in 317 incident bladder cancer patients and 317 controls. 16284380 2005
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 GeneticVariation disease BEFREE Neither transfection nor microinjection of the cells with the human DNA repair gene ERCC1, which is known not to correct any complementation groups of XP or CS, failed to correct the defect of these cells, indicating that they do not belong to the rodent complementation group 1. 7539208 1995
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 Biomarker disease BEFREE In the case of the remaining XP complementation groups (B, G, H and I), nuclear microinjection was used to introduce an ERCC-1 cDNA construct driven by an SV40 promoter into primary fibroblasts. 2918869 1989
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.370 GeneticVariation disease BEFREE Two UV-sensitive CHO mutant lines, UV20 and UV41, which belong to different genetic complementation groups, were fused with fibroblasts of xeroderma pigmentosum in various complementation groups. 4000167 1985