Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | A gender-specific association of the polymorphism Ile197Met in the kininogen 1 gene with plasma irbesartan concentrations in Chinese patients with essential hypertension. | 30283089 | 2018 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | However, despite the potential therapeutic benefit of increased natriuretic peptide and bradykinin levels, neprilysin inhibitor therapy has only modest efficacy in essential hypertension and heart failure. | 30283782 | 2018 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Differential gene expression of bradykinin receptors 1 and 2 in peripheral monocytes from patients with essential hypertension. | 24401952 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Bradykinin β2 receptor -58T/C gene polymorphism and essential hypertension: a meta-analysis. | 22900090 | 2012 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Both single-locus and haplotype analyses indicated the kininogen 1 gene was associated with essential hypertension and blood pressure traits in the Chinese male population. | 19330902 | 2009 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | To identify variants in the complete genomic sequence of the two subtypes of bradykinin receptors: B1 (BDKRB1) and B2 (BDKRB2) and to examine the association of these variants with essential hypertension. | 15643125 | 2005 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Relationship of bradykinin B2 receptor gene polymorphism with essential hypertension and left ventricular hypertrophy. | 15894833 | 2004 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | These results suggested that -58C allele of the human beta2 bradykinin receptor gene may be an independent risk factor for essential hypertension in the Chinese Han population. | 11409654 | 2001 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Hormone replacement therapy in postmenopausal women with essential hypertension increases circulating plasma levels of bradykinin. | 10560792 | 1999 |