Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 GeneticVariation disease BEFREE A gender-specific association of the polymorphism Ile197Met in the kininogen 1 gene with plasma irbesartan concentrations in Chinese patients with essential hypertension. 30283089 2018
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 AlteredExpression disease BEFREE However, despite the potential therapeutic benefit of increased natriuretic peptide and bradykinin levels, neprilysin inhibitor therapy has only modest efficacy in essential hypertension and heart failure. 30283782 2018
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 AlteredExpression disease BEFREE Differential gene expression of bradykinin receptors 1 and 2 in peripheral monocytes from patients with essential hypertension. 24401952 2014
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 GeneticVariation disease BEFREE Bradykinin β2 receptor -58T/C gene polymorphism and essential hypertension: a meta-analysis. 22900090 2012
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 GeneticVariation disease BEFREE Both single-locus and haplotype analyses indicated the kininogen 1 gene was associated with essential hypertension and blood pressure traits in the Chinese male population. 19330902 2009
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 GeneticVariation disease BEFREE To identify variants in the complete genomic sequence of the two subtypes of bradykinin receptors: B1 (BDKRB1) and B2 (BDKRB2) and to examine the association of these variants with essential hypertension. 15643125 2005
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 GeneticVariation disease BEFREE Relationship of bradykinin B2 receptor gene polymorphism with essential hypertension and left ventricular hypertrophy. 15894833 2004
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 GeneticVariation disease BEFREE These results suggested that -58C allele of the human beta2 bradykinin receptor gene may be an independent risk factor for essential hypertension in the Chinese Han population. 11409654 2001
Entrez Id: 3827
Gene Symbol: KNG1
KNG1
0.090 AlteredExpression disease BEFREE Hormone replacement therapy in postmenopausal women with essential hypertension increases circulating plasma levels of bradykinin. 10560792 1999