Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | Biomarker | disease | BEFREE | The autoantibodies against angiotensin AT1 receptors (AT1-AAs) in patients with essential hypertension exhibited an agonistic action like angiotensin II and maintained high blood pressure (BP). | 24131669 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Functional polymorphisms that predispose to increased basal GRK4 activity both decrease dopamine receptor activity and increase angiotensin II type 1 (AT1) receptor activity and are associated with essential hypertension in a number of different human cohorts. | 22407378 | 2012 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Correlation between HLA-DRB1, HLA-DQB1 polymorphism and autoantibodies against angiotensin AT(1) receptors in Chinese patients with essential hypertension. | 21557256 | 2011 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The A1166C polymorphism of the AT1 receptor gene is not associated with reduction of blood pressure after treatment with ACEI in patients with essential hypertension. | 18575418 | 2008 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | It has been reported that a polymorphism of the AT1 receptor gene (an A/C transversion at position 1166; A1166C) may be associated with essential hypertension (HT). | 12627871 | 2003 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Angiotensin II AT1 receptor gene polymorphism and microalbuminuria in essential hypertension. | 11336183 | 2001 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | We conducted a case-control study in a sample from the Japanese population to determine whether polymorphic markers in the 5'-flanking region of the AT 1 gene were associated with essential hypertension. | 11246471 | 2000 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | In 34 white patients with established mild to moderate essential hypertension (World Health Organization stage I or II, mean age 52 +/- 9 years) genotype analysis of GNB3 C825T polymorphism, insertion/deletion polymorphism of the ACE gene and 1166 A/C polymorphism of the AT1 receptor gene was performed. | 10526907 | 1999 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Of the described polymorphisms in the AT1-receptor gene, the A1166C transversion is associated with human essential hypertension. | 9717050 | 1998 |