Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1080
Gene Symbol: CFTR
CFTR 		0.100 CausalMutation disease CLINVAR
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.010 Biomarker disease BEFREE Fibrosing alveolitis (FA) is characterized by persistent inflammation and elevated production of tumor necrosis factor-alpha (TNF-alpha), interleukin-1 beta (IL-1beta), and interleukin-1 receptor antagonist (IL-1ra) in the lung. 10934117 2000
Entrez Id: 6275
Gene Symbol: S100A4
S100A4 		0.010 Biomarker disease BEFREE FSP1 also identified fibroblasts in lung biopsy specimens from patients with documented usual interstitial pneumonitis. 15618458 2005
Entrez Id: 51062
Gene Symbol: ATL1
ATL1 		0.010 Biomarker disease BEFREE FSP1 also identified fibroblasts in lung biopsy specimens from patients with documented usual interstitial pneumonitis. 15618458 2005
Entrez Id: 54106
Gene Symbol: TLR9
TLR9 		0.010 AlteredExpression disease BEFREE TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation. 18633634 2008
Entrez Id: 6775
Gene Symbol: STAT4
STAT4 		0.010 Biomarker disease BEFREE STAT4 and IRF5 act with additive effects in terms of susceptibility to both SSc and SSc-related fibrosing alveolitis. 19644887 2009
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1 		0.010 Biomarker disease BEFREE YKL-40, a chitinase-like protein mainly secreted by macrophages, neutrophils and epithelial cells, is increased in patients with idiopathic interstitial pneumonia and sarcoidosis. 27836954 2017
Entrez Id: 5265
Gene Symbol: SERPINA1
SERPINA1 		0.010 Biomarker disease BEFREE alpha 1-antitrypsin (alpha 1-A.T.) phenotypes were determined in 55 patients with rheumatoid arthritis (R.A.), 33 patients with R.A. and either obstructive airways disease or recurrent chest infections, 49 patients with fibrosing alveolitis (F.A.), 22 patients with R.A. and F.A., and 200 healthy controls. 72955 1977
Entrez Id: 2335
Gene Symbol: FN1
FN1 		0.010 GeneticVariation disease BEFREE Fibronectin gene polymorphisms associated with fibrosing alveolitis in systemic sclerosis. 9870923 1999
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR A child with severe pneumomediastinum and ABCA3 gene mutation: a puzzling connection. 22304854 2012
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B 		0.300 SusceptibilityMutation disease ORPHANET A common MUC5B promoter polymorphism and pulmonary fibrosis. 21506741 2011
Entrez Id: 931
Gene Symbol: MS4A1
MS4A1 		0.010 AlteredExpression disease BEFREE A patient with fibrosing alveolitis developed a diffuse large B-cell (DLBC) lymphoma that expressed CD20 and CD30. 15257558 2004
Entrez Id: 54474
Gene Symbol: KRT20
KRT20 		0.010 AlteredExpression disease BEFREE A patient with fibrosing alveolitis developed a diffuse large B-cell (DLBC) lymphoma that expressed CD20 and CD30. 15257558 2004
Entrez Id: 943
Gene Symbol: TNFRSF8
TNFRSF8 		0.010 AlteredExpression disease BEFREE A patient with fibrosing alveolitis developed a diffuse large B-cell (DLBC) lymphoma that expressed CD20 and CD30. 15257558 2004
Entrez Id: 1462
Gene Symbol: VCAN
VCAN 		0.010 Biomarker disease BEFREE A Serological Biomarker of Versican Degradation is Associated with Mortality Following Acute Exacerbations of Idiopathic Interstitial Pneumonia. 29728109 2018
Entrez Id: 727897
Gene Symbol: MUC5B
MUC5B 		0.300 SusceptibilityMutation disease ORPHANET A variant in the promoter of MUC5B and idiopathic pulmonary fibrosis. 21506748 2011
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR ABCA3 mutations associated with pediatric interstitial lung disease. 15976379 2005
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR Aberrant catalytic cycle and impaired lipid transport into intracellular vesicles in ABCA3 mutants associated with nonfatal pediatric interstitial lung disease. 18676873 2008
Entrez Id: 7015
Gene Symbol: TERT
TERT 		0.310 SusceptibilityMutation disease ORPHANET Adult-onset pulmonary fibrosis caused by mutations in telomerase. 17460043 2007
Entrez Id: 84549
Gene Symbol: MAK16
MAK16 		0.010 Biomarker disease BEFREE Anti-RNA binding protein positivity in idiopathic interstitial pneumonia. 30665514 2019
Entrez Id: 27303
Gene Symbol: RBMS3
RBMS3 		0.010 Biomarker disease BEFREE Anti-RNA binding protein positivity in idiopathic interstitial pneumonia. 30665514 2019
Entrez Id: 56902
Gene Symbol: PNO1
PNO1 		0.010 Biomarker disease BEFREE Anti-RNA binding protein positivity in idiopathic interstitial pneumonia. 30665514 2019
Entrez Id: 23524
Gene Symbol: SRRM2
SRRM2 		0.010 Biomarker disease BEFREE Anti-RNA binding protein positivity in idiopathic interstitial pneumonia. 30665514 2019
Entrez Id: 5725
Gene Symbol: PTBP1
PTBP1 		0.010 Biomarker disease BEFREE Anti-RNA binding protein positivity in idiopathic interstitial pneumonia. 30665514 2019
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.400 GeneticVariation disease CLINVAR ATP-binding cassette member A3 (E292V) gene mutation and pulmonary morbidity in very-low-birth-weight infants. 22145626 2012