Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 Biomarker disease BEFREE In response to 21 days of transverse aortic constriction, mice with cardiomyocyte-restricted inactivation (knockout) of the ANP receptor (guanylyl cyclase [GC]-A) or the downstream cGMP-dependent protein kinase I developed enhanced left ventricular hypertrophy and fibrosis together with contractile dysfunction. 25027872 2014
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 Biomarker disease RGD Vitamin D receptor activation, left ventricular hypertrophy and myocardial fibrosis. 24013683 2013
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 GeneticVariation disease BEFREE Our studies suggested that ANP gene promoter polymorphism is associated with left ventricular hypertrophy in hypertension. 20137368 2010
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 GeneticVariation disease LHGDN Atrial natriuretic peptide gene promoter polymorphism is associated with left ventricular hypertrophy in hypertension. 17672826 2008
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 Biomarker disease LHGDN The concentration of atrial and brain natriuretic peptide in patients with idiopathic hypertension. 17901852 2007
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 Biomarker disease RGD Increased natriuretic peptide receptor A and C gene expression in rats with pressure-overload cardiac hypertrophy. 16272201 2006
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 Biomarker disease BEFREE We describe an example of our own work where the combination of anatomical and a biochemical intermediate phenotypes have led to the identification of the natriuretic peptide precursor A (Nppa) gene as a candidate gene for left ventricular hypertrophy (LVH). 11882568 2002
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 Biomarker disease CTD_human Coordinate regulation of metabolic enzyme encoding genes during cardiac development and following carvedilol therapy in spontaneously hypertensive rats. 10755198 2000
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 Biomarker disease BEFREE Serum ACE activity and plasma concentrations of brain natriuretic peptide, a marker for left ventricular hypertrophy, were also monitored. 10335726 1999
Entrez Id: 4878
Gene Symbol: NPPA
NPPA
0.560 Biomarker disease CTD_human Molecular characteristics of cocaine-induced cardiomyopathy in rats. 9455993 1997