Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.560 | Biomarker | disease | BEFREE | In response to 21 days of transverse aortic constriction, mice with cardiomyocyte-restricted inactivation (knockout) of the ANP receptor (guanylyl cyclase [GC]-A) or the downstream cGMP-dependent protein kinase I developed enhanced left ventricular hypertrophy and fibrosis together with contractile dysfunction. | 25027872 | 2014 | ||||
|
0.560 | Biomarker | disease | RGD | Vitamin D receptor activation, left ventricular hypertrophy and myocardial fibrosis. | 24013683 | 2013 | ||||
|
0.560 | GeneticVariation | disease | BEFREE | Our studies suggested that ANP gene promoter polymorphism is associated with left ventricular hypertrophy in hypertension. | 20137368 | 2010 | ||||
|
0.560 | GeneticVariation | disease | LHGDN | Atrial natriuretic peptide gene promoter polymorphism is associated with left ventricular hypertrophy in hypertension. | 17672826 | 2008 | ||||
|
0.560 | Biomarker | disease | LHGDN | The concentration of atrial and brain natriuretic peptide in patients with idiopathic hypertension. | 17901852 | 2007 | ||||
|
0.560 | Biomarker | disease | RGD | Increased natriuretic peptide receptor A and C gene expression in rats with pressure-overload cardiac hypertrophy. | 16272201 | 2006 | ||||
|
0.560 | Biomarker | disease | BEFREE | We describe an example of our own work where the combination of anatomical and a biochemical intermediate phenotypes have led to the identification of the natriuretic peptide precursor A (Nppa) gene as a candidate gene for left ventricular hypertrophy (LVH). | 11882568 | 2002 | ||||
|
0.560 | Biomarker | disease | CTD_human | Coordinate regulation of metabolic enzyme encoding genes during cardiac development and following carvedilol therapy in spontaneously hypertensive rats. | 10755198 | 2000 | ||||
|
0.560 | Biomarker | disease | BEFREE | Serum ACE activity and plasma concentrations of brain natriuretic peptide, a marker for left ventricular hypertrophy, were also monitored. | 10335726 | 1999 | ||||
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0.560 | Biomarker | disease | CTD_human | Molecular characteristics of cocaine-induced cardiomyopathy in rats. | 9455993 | 1997 |