Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.550 | Biomarker | disease | BEFREE | Recent studies have indicated that monocyte chemoattractant protein-1 (MCP-1) plays an important role in the initiation and progression of ischaemic heart disease. | 31077149 | 2019 | ||||
|
0.550 | GeneticVariation | disease | BEFREE | Odds ratios (OR) with 95% confidence interval (CI) were used to evaluate the strength of associations between the MCP-1 A-2518G polymorphism (rs1024611) and IHD and IS susceptibilities. | 25413568 | 2015 | ||||
|
0.550 | GeneticVariation | disease | BEFREE | The aim of our work was to find if MCP-1 -2518 (A/G) single nucleotide polymorphism (SNP) influences somehow the serum concentrations of high-sensitive CRP (hsCRP) both in patients suffering from ischemic heart disease (IHD), myocardial infarction (MI), angina pectoris (AP), and hypertension (HT) and in control group of healthy subjects. | 19639050 | 2009 | ||||
|
0.550 | Biomarker | disease | BEFREE | However, the gene expression changes caused by signal transduction, triggered by MCP-1 binding to its receptor CCR2, and their possible role in the development of IHD are not understood. | 16574901 | 2006 | ||||
|
0.550 | Biomarker | disease | CTD_human | Cardioplegia prevents ischemia-induced transcriptional alterations of cytoprotective genes in rat hearts: a DNA microarray study. | 16214533 | 2005 | ||||
|
0.550 | Biomarker | disease | RGD | Prolonged cold ischemia in rat cardiac allografts promotes ischemia-reperfusion injury and the development of graft coronary artery disease in a linear fashion. | 16297799 | 2005 | ||||
|
0.550 | GeneticVariation | disease | BEFREE | Our data demonstrate that, in an Irish population, the MCP-1 -2518G/A polymorphism is not strongly associated with IHD. | 15245376 | 2004 | ||||
|
0.550 | Biomarker | disease | RGD | Neutralization of MCAF/MCP-1 is beneficial by preventing reperfusion injury in a rat model of myocardial ischemia and reperfusion. | 10068207 | 1999 |