Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 Biomarker disease BEFREE CONCLUSIONS EPCs can be used as a delivery vehicle for suppressor genes KAI1/CD82 to NPC, and the migration of KAI1/CD82 genetically engineered EPCs can inhibit NPC lung metastasis in a mouse model. 29755107 2018
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 AlteredExpression disease BEFREE The over-expression of CD82 in cancer cells led to the inhibition of experimentally induced lung metastases in mice and significantly inhibited the adhesion of these cells to human umbilical vein epithelial cells (HUVECs) in vitro. 25923697 2015
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 AlteredExpression disease BEFREE Results showed that CD82 expression inhibited melanoma cell-induced gap formation, melanoma cell extravasation in vitro and subsequent lung metastasis development in vivo. 23873025 2014
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 Biomarker disease BEFREE The sense KAI1 gene transfection into the cancer cells also inhibited their invasion and lung metastasis in the orthotopic liver cancer nude mice. 18028322 2008
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 Biomarker disease BEFREE Furthermore, the metastasis-suppression activity of KAI1 was significantly compromised in DARC knockout mice, whereas KAI1 completely abrogated pulmonary metastasis in wild-type and heterozygous littermates. 16862154 2006
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 GeneticVariation disease BEFREE Four (40%) of 10 osteosarcoma cases with no lung metastasis and one (25%) of four osteosarcoma cases with lung metastasis were positive for KAI1/CD82, respectively. 11569927 2001
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 Biomarker disease BEFREE Parental, vector-only transfectants and KAI1 transfectant clones were injected into the mammary fat pads and tail veins, respectively, of athymic nude mice and assessed for both spontaneous and experimental lung metastasis. 11431371 2001
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 Biomarker disease BEFREE The transmembrane 4 superfamily member KAI1 (CD82) has been shown to inhibit pulmonary metastases in experimental metastasis models of prostate cancer and melanoma. 10582691 1999
Entrez Id: 3732
Gene Symbol: CD82
CD82
0.090 Biomarker disease BEFREE Transfection of full-length kai-1 cDNA into MDA-MB-435 cells resulted in clones that did not have a significantly decreased in vivo incidence of lung metastases. 9496911 1998