Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE Interaction of HLA-DRB1* alleles and CTLA4 (+49 AG) gene polymorphism in Autoimmune Thyroid Disease. 29174716 2018
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE Association of Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Gene Polymorphisms with Autoimmune Thyroid Disease in Children and Adults: Case-Control Study. 27111218 2016
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE A common CTLA4 polymorphism confers susceptibility to autoimmune thyroid disease in celiac children. 18929517 2009
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE 49A/G and CT60 polymorphisms of the cytotoxic T-lymphocyte-associated antigen 4 gene associated with autoimmune thyroid disease. 19559744 2009
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 Biomarker disease BEFREE HLA haplotypes DRB1*03_DQB1*02 and DRB1*04_DQB1*0302, and allelic variation of the T cell regulatory gene cytotoxic T-lymphocyte-associated antigen-4 (CTLA4) and of the T cell activation gene protein tyrosine phosphatase, non-receptor type 22 (lymphoid) (PTPN22) have been associated with type 1 diabetes and autoimmune thyroid disease. 17334650 2007
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. 17504905 2007
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE Variation in the cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) gene plays a significant role in determining susceptibility to autoimmune thyroid disease and type 1 diabetes. 16325273 2006
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE The association of CTLA4 polymorphism with type 1 diabetes is concentrated in patients complicated with autoimmune thyroid disease: a multicenter collaborative study in Japan. 16352685 2006
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE One of the CTLA-4 SNPs, +6230G>A (CT60), has recently been reported to be related to susceptibility to type 1 diabetes and autoimmune thyroid disease. 17130562 2006
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 Biomarker disease BEFREE Association of the T-cell regulatory gene CTLA4 with Graves' disease and autoimmune thyroid disease in the Japanese. 14986169 2004
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE Association of the CTLA-4 gene 49 A/G polymorphism with type 1 diabetes and autoimmune thyroid disease in Japanese children. 12610047 2003
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 Biomarker disease BEFREE CTLA-4 and its role in autoimmune thyroid disease. 12914522 2003
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE Increasing evidence supports the genetic susceptibility for thyroid antibody (TAb) production in patients with autoimmune thyroid disease, and recently, it has been shown that the cytotoxic T lymphocyte antigen 4 (CTLA-4) gene is most likely a major TAb susceptibility gene. 12097196 2002
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE CTLA-4 and autoimmune thyroid disease: lack of influence of the A49G signal peptide polymorphism on functional recombinant human CTLA-4. 12202150 2002
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE Association of CTLA-4 gene A/G polymorphism in Japanese type 1 diabetic patients with younger age of onset and autoimmune thyroid disease. 10895849 2000
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 Biomarker disease BEFREE Cutting edge: a soluble form of CTLA-4 in patients with autoimmune thyroid disease. 10799854 2000
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE Association of autoimmune thyroid disease with microsatellite markers for the thyrotropin receptor gene and CTLA-4 in Japanese patients. 11081251 2000
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE The objective of this study was to examine the polymorphism in the cytotoxic T lymphocyte antigen-4 (CTLA-4) gene and its relationship with autoimmune thyroid disease in Koreans. 10907987 2000
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 Biomarker disease BEFREE This gene on chromosome 2q33 (designated IDDM12) is associated with susceptibility to both type 1 diabetes and autoimmune thyroid disease. 10782900 2000
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 Biomarker disease BEFREE We have genotyped 77 affected sib-pairs with autoimmune thyroid disease for eight polymorphic markers spanning the cytotoxic T lymphocyte antigen-4 ( CTLA-4 ) region of chromosome 2q31-q33, and for five markers spanning the major histocompatibility complex ( MHC ) region of chromosome 6p21. 10369864 1999
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4
0.100 GeneticVariation disease BEFREE No evidence for allelic association of a human CTLA-4 promoter polymorphism with autoimmune thyroid disease in either population-based case-control or family-based studies. 9861324 1998