Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.370 AlteredExpression disease BEFREE In the present work, we explored the carcinogenic activity and underlying mechanism of BRAF-activated noncoding RNA on pancreatic cancer <i>in vitro</i>. 31769353 2020
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.370 GeneticVariation disease BEFREE KRAS, NRAS and BRAF mutations are among the most important oncogenic drivers in many major cancer types, such as melanoma, lung, colorectal and pancreatic cancer. 29059158 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.370 GeneticVariation disease BEFREE The BRAF mutation was not detected in PC. 26927447 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.370 AlteredExpression disease BEFREE These deletions are mutually exclusive with KRAS mutations and occur in 4.21% of KRAS wild-type pancreatic cancer. siRNA knockdown in cells harboring BRAF deletions showed that the MAPK activity and cell growth are BRAF dependent. 26732095 2016
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.370 GeneticVariation disease BEFREE Oncogene-directed increased expression of Nrf2 is a new mechanism for the activation of the Nrf2 antioxidant program, and is evident in primary cells and tissues of mice expressing K-Ras(G12D) and B-Raf(V619E), and in human pancreatic cancer. 21734707 2011
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.370 GeneticVariation disease BEFREE Both BRAF and FBXW7 mutations functionally activate kinase effectors important in pancreatic cancer and extend the potential options for therapeutic targeting of kinases in the treatment of phenotypically distinct pancreatic adenocarcinoma subsets. 14507635 2003
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.370 GeneticVariation disease BEFREE We investigated the frequency of BRAF mutations in human pancreatic cancer specimens to determine its role in the development of pancreatic cancer. 12969789 2003
Entrez Id: 673
Gene Symbol: BRAF
BRAF
0.370 CausalMutation disease CGI