Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease BEFREE Notably, SNHG7 could enhance Wnt/β-catenin pathway activation to contribute to liver fibrosis, with an increase in T cell factor (TCF) activity and a reduction in P-β-catenin level. 31272073 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 AlteredExpression disease BEFREE In addition, we found that hBM-MSCs-Ex inhibited the expression of Wnt/β-catenin pathway components (PPARγ, Wnt3a, Wnt10b, β-catenin, WISP1, Cyclin D1), α-SMA, and Collagen I, in both HSCs and liver fibrosis tissue. 30885249 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease BEFREE Artesunate may inhibit liver fibrosis via the FAK/Akt/β-catenin pathway in LX-2 cells. 30326962 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease BEFREE In this review, we present recent insights into the correlation between Wnt/β-catenin signaling and liver fibrosis and discuss the antifibrotic effects of the cAMP-response element binding protein/β-catenin inhibitor PRI-724. 30308992 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease BEFREE Similarly, we found SENP2 has a negative effect on β-catenin as well as its downstream genes C-myc and CyclinD1 in liver fibrosis. 29535048 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 AlteredExpression disease BEFREE In conclusion, the present study demonstrated that NOR1 activates HSCs and contributes to liver fibrosis in vitro and this effect was achieved through the activation of the Wnt/β‑catenin pathway. 28791396 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease BEFREE Aberrant activated Wnt/β-catenin pathway is known to accelerate the development of liver fibrosis. microRNAs (miRNAs)-mediated Wnt/β-catenin pathway has been reported to be involved in HSC activation during liver fibrosis. 28391277 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease BEFREE In this study, we examined the expression of lncRNA-ATB/miR-200a, and their target gene β-Catenin in liver tissues of HCV patients and hepatic stellate cells (HSCs) to elucidate the possible role of lncRNA-ATB/miR-200a axis in HSC activation and development of liver fibrosis. 28302418 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease BEFREE However, whether miR-378a-3p suppresses Wnt/β-catenin pathway in liver fibrosis is largely unknown. 27832641 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease BEFREE The aim of this study is to investigate whether miR-200a could attenuate hepatic fibrosis partly through Wnt/β-catenin and TGF-β-dependant mechanisms. 24242045 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 AlteredExpression disease BEFREE A higher expression level of β-catenin was identified in the patients with high-grade hepatic fibrosis in comparison with that of the normal controls. 24691643 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease CTD_human Tumor formation in liver of conditional β-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen. 21047994 2011
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.500 Biomarker disease HPO