Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 183
Gene Symbol: AGT
AGT
0.370 Biomarker disease BEFREE In conclusion, these results demonstrated that perindopril, as ACE inhibitor, could grant a superior remedial nominee in preventing liver fibrosis progression through targeting angiotensin II formation. 31348596 2019
Entrez Id: 183
Gene Symbol: AGT
AGT
0.370 Biomarker disease BEFREE Angiotensin II (AngII) activates via angiotensin-II-type-I receptor (AT1R) Janus-kinase-2 (JAK2)/Arhgef1 pathway and subsequently RHOA/Rho-kinase (ROCK), which induces experimental and probably human liver fibrosis. 26385087 2017
Entrez Id: 183
Gene Symbol: AGT
AGT
0.370 Biomarker disease BEFREE Angiotensin II (Ang II) promotes hepatic fibrosis by increasing extracellular matrix (ECM) synthesis. 28798388 2017
Entrez Id: 183
Gene Symbol: AGT
AGT
0.370 Biomarker disease BEFREE Treatment with Ang-(1-7) inhibited mir-21, NLRP3 inflammasome, and liver fibrosis after bile duct ligation (BDL) or AngII infusion. 27502441 2017
Entrez Id: 183
Gene Symbol: AGT
AGT
0.370 AlteredExpression disease BEFREE In conclusion, shRNA expression vectors targeting rat AngII can decrease collagen synthesis, which would hopefully serve as a foundation for RNAi study of liver fibrosis in vivo. 20372825 2010
Entrez Id: 183
Gene Symbol: AGT
AGT
0.370 Biomarker disease BEFREE Angiotensin II type 1 (AT1) receptor blockers attenuate experimental liver fibrosis, yet their effects in human liver fibrosis are unknown. 19628656 2009
Entrez Id: 183
Gene Symbol: AGT
AGT
0.370 Biomarker disease CTD_human Inhibition of cGMP-specific phosphodiesterase type 5 reduces sodium excretion and arterial blood pressure in patients with NaCl retention and ascites. 15613622 2005
Entrez Id: 183
Gene Symbol: AGT
AGT
0.370 GeneticVariation disease BEFREE The combination of high AT and TGF-beta1 producing polymorphisms is associated with advanced hepatic fibrosis in obese patients with NAFLD. 14642613 2003