Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.510 Biomarker disease CTD_human The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. 24705251 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.510 Biomarker disease CTD_mouse PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies. 25119042 2014
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.510 GeneticVariation disease BEFREE TP53 mutations and 1p19q codeletion are the main molecular abnormalities recorded, respectively, in astrocytomas and oligodendrogliomas and in mixed gliomas. 22890969 2012
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.510 Biomarker disease CTD_human A germline variant in the TP53 polyadenylation signal confers cancer susceptibility. 21946351 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.510 Biomarker disease CTD_human In vitro drug response and molecular markers associated with drug resistance in malignant gliomas. 16899598 2006
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.310 Biomarker disease CTD_human Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome. 28122345 2017
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.310 Biomarker disease CTD_human Integrated genomic characterization of IDH1-mutant glioma malignant progression. 26618343 2016
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.310 Biomarker disease CTD_human Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. 25391653 2015
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.310 Biomarker disease CTD_human Mutational landscape and clonal architecture in grade II and III gliomas. 25848751 2015
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.310 GeneticVariation disease BEFREE However, the detection of divertive tumor cell clones in morphological distinct tumor components sharing IDH1- mutations as early event may provide insight into the tumorigenesis of true mixed gliomas. 22844452 2012
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.310 Biomarker disease CTD_human NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. 19901110 2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.310 Biomarker disease CTD_human The cyclooxygenase inhibitor indomethacin modulates gene expression and represses the extracellular matrix protein laminin gamma1 in human glioblastoma cells. 15561105 2005
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.310 AlteredExpression disease BEFREE The current study retrospectively reviewed 53 oligodendrogliomas and 7 oligodendroglioma-predominant oligoastrocytomas (mixed gliomas) for COX-2 expression and MIB-1 proliferative index (by immunohistochemistry) and for chromosome 1p status (by fluorescence in situ hybridization). 14508834 2003
Entrez Id: 23650
Gene Symbol: TRIM29
TRIM29
0.300 Biomarker disease CTD_human ATDC contributes to sustaining the growth and invasion of glioma cells through regulating Wnt/β-catenin signaling. 30929997 2019
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.300 Biomarker disease CTD_human Ras-Induced miR-146a and 193a Target Jmjd6 to Regulate Melanoma Progression. 30619488 2018
Entrez Id: 54739
Gene Symbol: XAF1
XAF1
0.300 Biomarker disease CTD_human Epigenetic silencing of XAF1 in high-grade gliomas is associated with IDH1 status and improved clinical outcome. 28122345 2017
Entrez Id: 4602
Gene Symbol: MYB
MYB
0.300 Biomarker disease CTD_human MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. 26829751 2016
Entrez Id: 9444
Gene Symbol: QKI
QKI
0.300 Biomarker disease CTD_human MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism. 26829751 2016
Entrez Id: 7515
Gene Symbol: XRCC1
XRCC1
0.300 Biomarker disease CTD_human Association between the XRCC1 Arg194Trp polymorphism and glioma risk: an updated meta-analysis. 25227852 2014
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
0.300 Biomarker disease CTD_human Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma. 24705252 2014
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
0.300 Biomarker disease CTD_human The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. 24705251 2014
Entrez Id: 4763
Gene Symbol: NF1
NF1
0.300 Biomarker disease CTD_human PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies. 25119042 2014
Entrez Id: 8493
Gene Symbol: PPM1D
PPM1D
0.300 Biomarker disease CTD_human Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas. 24880341 2014
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1
0.300 Biomarker disease CTD_human Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. 24705254 2014
Entrez Id: 546
Gene Symbol: ATRX
ATRX
0.300 Biomarker disease CTD_human The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. 24705251 2014