Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.440 Biomarker disease BEFREE Knockdown of the expression of PTEN altered the expression of p‑AKT, p‑glycogen synthase kinase 3β and β‑catenin, which are genes that have been reported to be involved in the development of gastric adenocarcinoma. 29512701 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.440 AlteredExpression disease BEFREE DKK1 and Wnt/β-catenin-dependent activation of MMP7 induces T-DM1 resistance and leads to the poor prognosis of gastric adenocarcinoma, which might be a novel potential therapeutical target for T-DM1 resistant gastric adenocarcinoma. 30501604 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.440 AlteredExpression disease BEFREE Specific indexes include the pathological characteristics of gastric neoplasia, Helicobacter pylori infection, β-catenin mutation status, and methylation status of Wnt antagonist genes.There was significant difference of β-catenin expression in patient with NGT, LGA, HGA, and GAC, the results respectively were 4.2%, 41.7%, 83.3%, and 91.7%. 30593147 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.440 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.440 Biomarker disease BEFREE Expression of APC, β-catenin and E-cadherin in Tunisian patients with gastric adenocarcinoma: clinical significance. 24197976 2014
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.440 CausalMutation disease CGI
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
0.410 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
0.410 AlteredExpression disease BEFREE Immunohistochemical expression of EGFR and HER3 was analysed in all primary tumours and a subset of lymph node metastases in a consecutive cohort of 174 patients with adenocarcinoma of the stomach, cardia and esophagus. 26844548 2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3
0.410 CausalMutation disease CGI
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
0.400 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 4893
Gene Symbol: NRAS
NRAS
0.400 CausalMutation disease CGI
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
0.320 Biomarker disease BEFREE ROS1 is a receptor tyrosine kinase that has recently been shown to undergo genetic rearrangements in a variety of human cancers, including glioblastoma, non-small cell lung cancer (NSCLC), cholangiocarcinoma, ovarian cancer, gastric adenocarcinoma, colorectal cancer, inflammatory myofibroblastic tumor, angiosarcoma, and epithelioid hemangioendothelioma. 23719267 2013
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
0.320 Biomarker disease BEFREE Identification of ROS1 rearrangement in gastric adenocarcinoma. 23400546 2013
Entrez Id: 6098
Gene Symbol: ROS1
ROS1
0.320 GeneticVariation disease UNIPROT
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2
0.310 AlteredExpression disease BEFREE However, EphA2 and ephrinA1 are highly expressed in human cancers including gastric adenocarcinoma. 29948146 2018
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
0.310 Biomarker disease BEFREE The purpose of this study was to examine the inhibitory effects of PlGF knockdown on cell proliferation, apoptosis and migration through p38 mitogen-activated protein kinase (p38MAPK) and PI3K pathways in human adenocarcinoma gastric cell line (AGS). 26968576 2016
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
0.310 PosttranslationalModification disease BEFREE Microsatellite instability of papillary subtype of human gastric adenocarcinoma and hMLH1 promoter hypermethylation in the surrounding mucosa. 11350605 2001
Entrez Id: 1432
Gene Symbol: MAPK14
MAPK14
0.310 GeneticVariation disease UNIPROT
Entrez Id: 4292
Gene Symbol: MLH1
MLH1
0.310 CausalMutation disease CGI
Entrez Id: 1969
Gene Symbol: EPHA2
EPHA2
0.310 GeneticVariation disease UNIPROT
Entrez Id: 3702
Gene Symbol: ITK
ITK
0.300 GeneticVariation disease UNIPROT
Entrez Id: 284656
Gene Symbol: EPHA10
EPHA10
0.300 GeneticVariation disease UNIPROT
Entrez Id: 7273
Gene Symbol: TTN
TTN
0.300 GeneticVariation disease UNIPROT
Entrez Id: 10188
Gene Symbol: TNK2
TNK2
0.300 GeneticVariation disease UNIPROT
Entrez Id: 5563
Gene Symbol: PRKAA2
PRKAA2
0.300 GeneticVariation disease UNIPROT