Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.400 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.400 CausalMutation disease CGI
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.400 Biomarker disease HPO
Entrez Id: 613
Gene Symbol: BCR
BCR
0.300 GeneticVariation disease UNIPROT
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
0.300 GeneticVariation disease UNIPROT
Entrez Id: 5979
Gene Symbol: RET
RET
0.300 GeneticVariation disease UNIPROT
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 AlteredExpression disease BEFREE BAI‑1 may be involved in the negative regulation of BTCC microvascular proliferation, and its expression may be associated with a reduction in p53 mutations. 26129954 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.200 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE Deletion/duplication mutation screening of TP53 gene in patients with transitional cell carcinoma of urinary bladder using multiplex ligation-dependent probe amplification. 26685928 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE Loss of p53 and acquisition of angiogenic microRNA profile are insufficient to facilitate progression of bladder urothelial carcinoma in situ to invasive carcinoma. 21388952 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE Implications of p53 gene mutations on patient survival in transitional cell carcinoma of the bladder: a long-term study. 18367096 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE Expression of vascular endothelial growth factor, receptor KDR and p53 protein in transitional cell carcinoma of the bladder. 18645275 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE Clinical implications of the MDM2 SNP309 and p53 Arg72Pro polymorphisms in transitional cell carcinoma of the bladder. 18575717 2008
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE TGF-betaRII, BAX, IGFIIR, caspase-5, hMSH3 and hMSH6 alterations are not associated with microsatellite instability or p53 mutations in invasive urothelial carcinoma of the urinary bladder. 17676485 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE To address to the question whether promoter methylation of novel p53 effector genes is a common event in transitional cell carcinoma of the bladder, we selected the p53 target genes apoptotic protein-activating factor (APAF-1), Caspase 8 (CASP-8), death-associated protein kinase, (DAPK-1) and insulin-like growth-factor-binding protein-3 (IGFBP-3), performing quantitative methylation-specific real-time PCR. 16642478 2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 AlteredExpression disease BEFREE Assessment of the transcriptional activity of p53 improves the prediction of recurrence in superficial transitional cell carcinoma of the bladder. 16000567 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE In the present study we correlate the p53 gene mutations in tumour tissue with urine sediment using a functional assay in yeast, and relate the p53 status to the outcome in a group of patients with transitional cell carcinoma of the bladder. 15308588 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE Future analyses of the progress of patients with superficial bladder transitional cell carcinoma and mutated p53 will help clarify this aspect. 15539839 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE Protein expression and gene copy number analysis of topoisomerase 2alpha, HER2 and P53 in minimally invasive urothelial carcinoma of the urinary bladder--a multitissue array study with prognostic implications. 15816547 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.200 AlteredExpression disease BEFREE HER2/neu gene amplification and protein overexpression in G3 pT2 transitional cell carcinoma of the bladder: a role for anti-HER2 therapy? 14687790 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE The expression pattern of PAX5 in the tissue of superficial bladder transitional cell carcinoma (TCC), its prognostic value and its correlation with p53 immunohistochemistry and p53 mutation analysis were evaluated. 14577491 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE We outline the basic constitutive functions of p53 and summarize its current role in the management of transitional cell carcinoma of the bladder. 12629332 2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.200 AlteredExpression disease BEFREE HER2/neu overexpression in the development of muscle-invasive transitional cell carcinoma of the bladder. 14520464 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE Overexpression of c-met as a prognostic indicator for transitional cell carcinoma of the urinary bladder: a comparison with p53 nuclear accumulation. 11896103 2002