Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.140 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.140 AlteredExpression disease BEFREE AKT, EGFR, C-ErbB-2, and C-kit expression in uterine carcinosarcoma. 23896716 2013
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.140 AlteredExpression disease BEFREE Demonstration of HER-2/neu overexpression and amplification in uterine carcinosarcoma may represent the first rationale step for further investigations. 16445668 2006
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.140 AlteredExpression disease BEFREE We describe HER-2/neu overexpression and her-2/neu oncogene amplification in a case of uterine carcinosarcoma occurring in a 46-year-old women who had undergone mastectomy and a 2-year postoperative treatment with tamoxifen for invasive breast cancer. 15901136 2005
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.140 GeneticVariation disease BEFREE The current results suggest absence of ERBB-2 overexpression in uterine leiomyosarcoma, uterine adenosarcoma, and endometrial stromal sarcoma, whereas the ERBB-2 gene might have a biologic role in uterine carcinosarcoma and undifferentiated uterine sarcomas. 15581967 2004
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.120 GeneticVariation disease BEFREE In addition to TP53, other recurrently mutated genes harboring putative driver or loss-of-function mutations included PTEN, FBXW7, FGFR2, KRAS, PIK3CA and CTNNB1, genes known to be involved in UCS. 30194005 2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.120 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.120 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.120 GeneticVariation disease BEFREE Molecular alterations of PIK3CA in uterine carcinosarcoma, clear cell, and serous tumors. 25078343 2014
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA 		0.120 GeneticVariation disease BEFREE The expression of AKT, epithelial growth factor receptor, C-Kit, and C-ErbB-2 were studied by immunohistochemistry and exons 9 and 20 of PIK3CA gene were sequences in a cohort of 37 UCS, including 23 early-stage (I and II) and 14 late-stage (III and IV) tumors. 23896716 2013
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.120 Biomarker disease BEFREE DNA mismatch repair and TP53 defects are early events in uterine carcinosarcoma tumorigenesis. 16810312 2006
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7 		0.110 Biomarker disease BEFREE Genomic analysis showed that most tumors spontaneously acquired <i>Trp53</i> mutations, pointing to a triad of pathways (p53, PI3K, and Fbxw7) as the critical combination underpinning uterine carcinosarcoma, and to Fbxw7 as a key driver of this enigmatic endometrial cancer type. 31772025 2019
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.110 Biomarker disease BEFREE Tumor Mutational Burden Guides Therapy in a Treatment Refractory <i>POLE-</i>Mutant Uterine Carcinosarcoma. 29386312 2018
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.110 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 55294
Gene Symbol: FBXW7
FBXW7 		0.110 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5295
Gene Symbol: PIK3R1
PIK3R1 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5518
Gene Symbol: PPP2R1A
PPP2R1A 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 7307
Gene Symbol: U2AF1
U2AF1 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 2065
Gene Symbol: ERBB3
ERBB3 		0.100 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C 		0.050 Biomarker disease BEFREE This is a secondary analysis of a previous multicenter retrospective study examining 906 women with stage I-IV UCS who underwent primary hysterectomy. 31196490 2019
Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C 		0.050 Biomarker disease BEFREE This was a secondary analysis of a prior multicenter retrospective study that examined women with stage I-IV UCS who underwent primary hysterectomy. 29971677 2018
Entrez Id: 80316
Gene Symbol: PPP1R2C
PPP1R2C 		0.050 Biomarker disease BEFREE This is a secondary analysis of multicenter retrospective study examining women with stages I-IV UCS who underwent primary surgery. 30217299 2018