Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE Germline BRCA1 and BRCA2 mutations are the most common gene mutations in familial pancreatic adenocarcinoma. 31612916 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE The study was powered to identify genes with a cumulative pathogenic variant prevalence of at least 3%, which includes the most prevalent PC susceptibility gene, BRCA2. 31469826 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE Are BRCA1 and BRCA2 gene mutation patients underscreened for pancreatic adenocarcinoma? 30636051 2019
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE BRCA1/BRCA2 germ line (GL) mutation carriers with pancreatic adenocarcinoma (PDAC) may have distinct outcomes. 28183138 2017
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE Screening for Pancreatic Adenocarcinoma in BRCA2 Mutation Carriers: Results of a Disease Simulation Model. 26844277 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE Clinical outcomes in pancreatic adenocarcinoma associated with BRCA-2 mutation. 25304989 2015
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE The 2 patients with pancreatic adenocarcinoma both had breast cancer and BRCA2 mutations. 24622079 2014
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE High prevalence of BRCA1 and BRCA2 germline mutations with loss of heterozygosity in a series of resected pancreatic adenocarcinoma and other neoplastic lesions. 23658460 2013
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE We selected 29 Italian PC patients from a case-control study of PC according to their personal and family history of both PC and breast/ovarian cancer (BC/OC) and tested them for presence of germline mutations in BRCA1, BRCA2 and PALB2. 21989927 2012
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 Biomarker disease BEFREE We report a case of pancreatic adenocarcinoma arising in a 60-year-old carrier of a rare BRCA2 (1153insertionT) germline mutation. 21613821 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE BRCA1 and BRCA2 germline mutations are associated with an elevated risk for pancreas adenocarcinoma (PAC). 21934105 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 Biomarker disease BEFREE Capan-1 is a well-characterised BRCA2-deficient human cell line isolated from a liver metastasis of a pancreatic adenocarcinoma. 21750719 2011
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE The prognostic significance of germline BRCA1 and BRCA2 mutations in Jewish patients with pancreatic adenocarcinoma (PAC) is unknown. 19064968 2009
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE Although the association of germline BRCA2 mutations with pancreatic adenocarcinoma is well established, the role of BRCA1 mutations is less clear. 18762988 2008
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 GeneticVariation disease BEFREE A family history of pancreatic adenocarcinoma is not common in patients with this disease, but recent research has shown that pancreatic adenocarcinoma can be a feature of cancer susceptibility syndromes associated with germline mutations in p16, BRCA1, BRCA2, and APC. 8950667 1996
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 Biomarker disease HPO