×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
Germline BRCA1 and BRCA2 mutations are the most common gene mutations in familial pancreatic adenocarcinoma .
31612916
2019
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
The study was powered to identify genes with a cumulative pathogenic variant prevalence of at least 3%, which includes the most prevalent PC susceptibility gene, BRCA2 .
31469826
2019
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
Are BRCA1 and BRCA2 gene mutation patients underscreened for pancreatic adenocarcinoma ?
30636051
2019
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
BRCA1/BRCA2 germ line (GL) mutation carriers with pancreatic adenocarcinoma (PDAC) may have distinct outcomes.
28183138
2017
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
Screening for Pancreatic Adenocarcinoma in BRCA2 Mutation Carriers: Results of a Disease Simulation Model.
26844277
2015
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
Clinical outcomes in pancreatic adenocarcinoma associated with BRCA-2 mutation.
25304989
2015
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
The 2 patients with pancreatic adenocarcinoma both had breast cancer and BRCA2 mutations.
24622079
2014
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
High prevalence of BRCA1 and BRCA2 germline mutations with loss of heterozygosity in a series of resected pancreatic adenocarcinoma and other neoplastic lesions.
23658460
2013
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
We selected 29 Italian PC patients from a case-control study of PC according to their personal and family history of both PC and breast/ovarian cancer (BC/OC) and tested them for presence of germline mutations in BRCA1, BRCA2 and PALB2.
21989927
2012
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
Biomarker
disease
BEFREE
We report a case of pancreatic adenocarcinoma arising in a 60-year-old carrier of a rare BRCA2 (1153insertionT ) germline mutation.
21613821
2011
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
BRCA1 and BRCA2 germline mutations are associated with an elevated risk for pancreas adenocarcinoma (PAC).
21934105
2011
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
Biomarker
disease
BEFREE
Capan-1 is a well-characterised BRCA2 -deficient human cell line isolated from a liver metastasis of a pancreatic adenocarcinoma .
21750719
2011
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
The prognostic significance of germline BRCA1 and BRCA2 mutations in Jewish patients with pancreatic adenocarcinoma (PAC) is unknown.
19064968
2009
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
Although the association of germline BRCA2 mutations with pancreatic adenocarcinoma is well established, the role of BRCA1 mutations is less clear.
18762988
2008
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
GeneticVariation
disease
BEFREE
A family history of pancreatic adenocarcinoma is not common in patients with this disease, but recent research has shown that pancreatic adenocarcinoma can be a feature of cancer susceptibility syndromes associated with germline mutations in p16, BRCA1, BRCA2 , and APC.
8950667
1996
×
Entrez Id:
675
Gene Symbol:
BRCA2
BRCA2
0.200
Biomarker
disease
HPO