×
Entrez Id:
4255
Gene Symbol:
MGMT
MGMT
0.510
GeneticVariation
disease
BEFREE
Our data indicate, that in addition to the histological and immunohistochemical evaluation, investigation of MGMT promoter methylation and in particular BRAF V600E mutations represent reliable additional tools to sustain differentiation of gcGBM from PXA on a molecular basis.
27253461
2016
×
Entrez Id:
4255
Gene Symbol:
MGMT
MGMT
0.510
Biomarker
disease
ORPHANET
A study of clinico-pathological parameters and O⁶-methylguanine DNA methyltransferase (MGMT) promoter methylation status in the prognostication of gliosarcoma.
22380407
2012
×
Entrez Id:
4255
Gene Symbol:
MGMT
MGMT
0.510
Biomarker
disease
CTD_human
Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastoma with a mesenchymal-epithelial transition inhibitor.
22162573
2012
×
Entrez Id:
4255
Gene Symbol:
MGMT
MGMT
0.510
Biomarker
disease
ORPHANET
O6-methylguanine DNA methyltransferase status determined by promoter methylation and immunohistochemistry in gliosarcoma and their clinical implications.
20556478
2011
×
Entrez Id:
4255
Gene Symbol:
MGMT
MGMT
0.510
Biomarker
disease
CTD_human
MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma.
20131314
2010
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.500
Biomarker
disease
CTD_human
EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.
26455392
2015
SEPTIN14
0.500
FusionGene
disease
ORPHANET
Systematic exploration of natural and synthetic flavonoids for the inhibition of Staphylococcus aureus biofilms.
24071942
2013
×
Entrez Id:
8216
Gene Symbol:
LZTR1
LZTR1
0.500
SomaticCausalMutation
disease
ORPHANET
The FSHD2 gene SMCHD1 is a modifier of disease severity in families affected by FSHD1.
24075187
2013
SEPTIN14
0.500
Biomarker
disease
CTD_human
The integrated landscape of driver genomic alterations in glioblastoma.
23917401
2013
SEPTIN14
0.500
FusionGene
disease
ORPHANET
The FSHD2 gene SMCHD1 is a modifier of disease severity in families affected by FSHD1.
24075187
2013
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.500
Biomarker
disease
CTD_human
The integrated landscape of driver genomic alterations in glioblastoma.
23917401
2013
×
Entrez Id:
8216
Gene Symbol:
LZTR1
LZTR1
0.500
SomaticCausalMutation
disease
ORPHANET
Genomics informs glioblastoma biology.
24071842
2013
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.500
FusionGene
disease
ORPHANET
Systematic exploration of natural and synthetic flavonoids for the inhibition of Staphylococcus aureus biofilms.
24071942
2013
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.500
FusionGene
disease
ORPHANET
The FSHD2 gene SMCHD1 is a modifier of disease severity in families affected by FSHD1.
24075187
2013
×
Entrez Id:
8216
Gene Symbol:
LZTR1
LZTR1
0.500
Biomarker
disease
CTD_human
The integrated landscape of driver genomic alterations in glioblastoma.
23917401
2013
×
Entrez Id:
1956
Gene Symbol:
EGFR
EGFR
0.500
Biomarker
disease
CTD_human
Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034.
19204207
2009
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.340
GeneticVariation
disease
BEFREE
Previously, single-gene study identified genetic changes in TP53 , PTEN and TERT promoter mutation in gcGBM .
30861589
2019
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.340
GeneticVariation
disease
BEFREE
Fifty-nine percent of gcGB samples but only 18% of the GB samples showed p53 mutations.
20467329
2010
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.340
Biomarker
disease
ORPHANET
Long-term survival with glioblastoma multiforme.
17785346
2007
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.340
Biomarker
disease
BEFREE
This article gives an outline of molecular biological approaches to analysis of neurological disorders such as giant cell glioblastoma (GGBM ) and amyotrophic lateral sclerosis (ALS), and their respective animal models: p53 knockout mice for GGBM and mutant superoxide dismutase-1 transgenic mice for ALS.
12564775
2002
×
Entrez Id:
7157
Gene Symbol:
TP53
TP53
0.340
GeneticVariation
disease
BEFREE
In this study, we assessed p53 mutations and EGFR expression in the giant cell glioblastoma .
9370234
1997
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
0.310
GeneticVariation
disease
BEFREE
IDH1 R132 and IDH R172 mutations were not present in any of the PXA and gcGBM cases.
27253461
2016
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
0.310
Biomarker
disease
ORPHANET
An integrated genomic analysis of human glioblastoma multiforme.
18772396
2008
×
Entrez Id:
1950
Gene Symbol:
EGF
EGF
0.310
Biomarker
disease
CTD_human
Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones.
16598420
2006
×
Entrez Id:
1950
Gene Symbol:
EGF
EGF
0.310
AlteredExpression
disease
BEFREE
p53 mutations versus EGF receptor expression in giant cell glioblastomas .
9370234
1997