Gene: BDNF ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 AlteredExpression disease BEFREE The present study aimed to evaluate the effects of treatment with lithium (Li) and valproate (VPA) on behaviors and brain BDNF, NGF, NT-3, NT-4 and GDNF levels in mice submitted to paradoxical sleep deprivation (PSD), which induces an animal model of mania. 31574363 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 Biomarker disease BEFREE The aim of the present study was to detect TL, human telomerase reverse transcriptase (hTERT), and brain derived neurotrophic factor (BDNF) in severe mania and subsequent remission. 28700015 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 AlteredExpression disease BEFREE Cognitive flexibility impairment and reduced frontal cortex BDNF expression in the ouabain model of mania. 27267245 2017
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 AlteredExpression disease BEFREE The change in BDNF levels between mania and remission could be adaptive and used to follow the progression of BD. 27138695 2016
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 AlteredExpression disease BEFREE In meta-regression analyses, BDNF levels additionally negatively correlate with the severity of both manic and depressive symptoms. 26621529 2015
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 GeneticVariation disease BEFREE Sixty-six subjects with BD (41 in manic and 25 in depressive episodes) and 78 healthy volunteers were genotyped for BDNF Val(66)Met and tested for creativity using the Barrow Welsh Art Scale (BWAS) and neuropsychological tests. 22484201 2012
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 Biomarker disease BEFREE Our results did not support the BDNF gene link to antidepressant-induced mania, like a previous study with a smaller sample has already suggested. 20483468 2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 Biomarker disease CTD_human Association studies of the BDNF and the NTRK2 gene polymorphisms with prophylactic lithium response in bipolar patients. 19018715 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 PosttranslationalModification disease BEFREE However, a larger sample would allow for greater power to determine smaller effects of the BDNF gene in antidepressant-induced mania. 17680923 2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 Biomarker disease BEFREE Serum BDNF is low in proportion to the severity of mania and depression and increases with clinical improvement. 17239400 2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		0.390 Biomarker disease CTD_human Molecular abnormalities of the hippocampus in severe psychiatric illness: postmortem findings from the Stanley Neuropathology Consortium. 14708030 2004