Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE This is the first prospective cohort study to evaluate a detection of MM by calretinin and its combination with mesothelin up to about a year before clinical diagnosis. 30254313 2018
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE Assessment of potential predictors of calretinin and mesothelin to improve the diagnostic performance to detect malignant mesothelioma: results from a population-based cohort study. 29025836 2017
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE Comparison of the Diagnostic Performance of Fibulin-3 and Mesothelin in Patients with Pleural Effusions from Malignant Mesothelioma. 28314308 2017
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE Midkine is a potential novel marker for malignant mesothelioma with different prognostic and diagnostic values from mesothelin. 28335760 2017
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE Molecular markers like calretinin and mesothelin are promising tools to improve and supplement the diagnosis of MM and warrant further validation in a prospective study. 28558669 2017
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 AlteredExpression disease BEFREE In malignant mesothelioma, overall survival was significantly longer in the cohort of patients with diffuse membranous expression of mesothelin (P < 0.001). 28460459 2017
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE Here we review the most promising biomarkers in MM to date: mesothelin, soluble mesothelin-related peptides (SMRPs), megakaryocyte potentiating factor (MPF), Osteopontin (OPN), Fibulin-3, high mobility group B1 (HMGB1), microRNAs (miRNAs), multiplex protein signatures. 28713671 2017
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease CTD_human Evaluation of New Biomarkers in the Prediction of Malignant Mesothelioma in Subjects with Environmental Asbestos Exposure. 27032653 2016
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE Combined circulating epigenetic markers to improve mesothelin performance in the diagnosis of malignant mesothelioma. 26431916 2015
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE The single-chain IL12-SS1 (Fv) immunocytokine bound native mesothelin proteins on malignant mesothelioma (NCI-H226) and ovarian (OVCAR-3) cells as well as recombinant mesothelin on A431/H9 cells. 24260587 2013
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease BEFREE Association of MiR-126 with soluble mesothelin-related peptides, a marker for malignant mesothelioma. 21483773 2011
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 AlteredExpression disease BEFREE These findings suggested that hypomethylation of the MSLN promoter may be specifically associated with the formation of MM, regardless of its expression status, and that the expression of mesothelin protein was lost in the sarcomatoid type by some unknown posttranscriptional regulatory mechanism. 20573372 2010
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 AlteredExpression disease BEFREE Ovarian cancer and malignant mesothelioma frequently express both mesothelin and CA125 (also known as MUC16) at high levels on the cell surface. 19075018 2009
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 Biomarker disease CTD_human Serum levels of soluble mesothelin-related peptides in malignant and nonmalignant asbestos-related pleural disease: relation with past asbestos exposure. 19190155 2009
Entrez Id: 10232
Gene Symbol: MSLN
MSLN
0.400 AlteredExpression disease BEFREE Anti-tumor activity of K1-LysPE38QQR, an immunotoxin targeting mesothelin, a cell-surface antigen overexpressed in ovarian cancer and malignant mesothelioma. 10916757 2000