Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 GeneticVariation disease BEFREE In conclusion, we present a novel genome-wide candidate SNP for PDAC risk (TERT-rs2736100), a completely new signal (NAF1-rs7675998) approaching genome-wide significance and we report a strong association between the teloscore and risk of pancreatic cancer, suggesting that telomeres are a potential risk factor for pancreatic cancer. 30325019 2019
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 Biomarker disease BEFREE The TERT hypermethylated oncologic region predicts recurrence and survival in pancreatic cancer. 29019414 2017
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 Biomarker disease CTD_human Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer. 26098869 2015
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 GeneticVariation disease BEFREE This meta-analysis suggests that T allele of CLPTM1L-telomerase reverse transcriptase rs401681 polymorphism is associated with an increased PC risk, especially among Chinese. 25284078 2015
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 Biomarker disease BEFREE We performed an in-depth analysis of genetic variability of the telomerase reverse transcriptase (TERT) and the telomerase RNA component (TERC) genes, in 5,550 subjects with pancreatic cancer and 7,585 controls from the PANcreatic Disease ReseArch (PANDoRA) and the PanScan consortia. 25940397 2015
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 Biomarker disease CTD_human Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. 25086665 2014
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 GeneticVariation disease BEFREE Our data suggests that the T allele of rs401681 in CLPTM1L-TERT locus predisposes its carriers to pancreatic cancer, and further research into the function of CLPTM1L-TERT locus and its potential biological mechanism association may be warranted. 24577890 2014
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 AlteredExpression disease BEFREE The COOH-terminal half fragment of CPE (C-CPE) enhances the effectiveness of clinically relevant chemotherapies and can be used as a carrier for drugs and other bacterial toxins to claudin-4-positive cancer cells. hTERT-HPDE cells, in which the human telomerase reverse transcriptase (hTERT) gene is introduced into normal HPDE cells, may be a useful model of normal HPDE cells not only for physiological regulation of claudin-4 expression but also for developing safer and more effective therapeutic methods targeting claudin-4 in pancreatic cancer. 22800288 2012
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 GeneticVariation disease BEFREE Single nucleotide polymorphisms (SNPs) in ABO, sonic hedgehog (SHH), telomerase reverse transcriptase (TERT), nuclear receptor subfamily 5, group A, member 2 (NR5A2) were found to be associated with pancreatic cancer risk. 22125638 2011
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 PosttranslationalModification disease BEFREE Positive regulation of human telomerase reverse transcriptase gene expression and telomerase activity by DNA methylation in pancreatic cancer. 19194757 2009
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 Biomarker disease BEFREE Quantitative analysis of human telomerase reverse transcriptase in pancreatic cancer. 16609017 2006
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 AlteredExpression disease BEFREE Quantitative assessment of telomerase activity and human telomerase reverse transcriptase messenger RNA levels in pancreatic juice samples for the diagnosis of pancreatic cancer. 15788678 2005
Entrez Id: 7015
Gene Symbol: TERT
TERT
0.400 Biomarker disease BEFREE To clarify growth inhibition in pancreatic cancer cells by interference with the hTR component of the telomerase reverse transcriptase enzymatic complex. 12215291 2002