Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.070 AlteredExpression disease BEFREE Arguably the MYC activity gain is the most constantly observed phenomenon (>70% of cases) in transformed FL/MALT/CLL (Richter's transformation) and co-occurs with specific aberrations such as the loss of p53, CDKN2A/B, or gain of BCL2/BCL6. 31631728 2020
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.070 GeneticVariation disease BEFREE Molecular lesions of regulators of tumor suppression (TP53), cell cycle (CDKN2A), and cell proliferation (NOTCH1, MYC) overall account for ~90% of RS and may be responsible for the aggressive clinical phenotype observed in this disease because of the combined effect of chemoresistance and rapid disease kinetics. 27040710 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.070 GeneticVariation disease BEFREE Molecular lesions of tumor suppression regulators (TP53), cell cycle (CDKN2A) and cell proliferation (NOTCH1, MYC) overall account for ∼90% of RS and may be responsible for its aggressive clinical phenotype. 27742070 2016
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.070 AlteredExpression disease BEFREE Here we report three cases of RS with overexpression of c-MYC. 26261666 2015
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.070 Biomarker disease BEFREE Cytogenetic and flow cytometry evaluation of Richter syndrome reveals MYC, CDKN2A, IGH alterations with loss of CD52, CD62L and increase of CD71 antigen expression as the most frequent recurrent abnormalities. 25511139 2015
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.070 Biomarker disease BEFREE However, several observations suggest that MYC pathway might be involved in RS. 20014148 2010
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.070 Biomarker disease BEFREE Increased C-MYC oncogene copy number detected with combined modified comparative genomic hybridization and FISH analysis in a Richter syndrome case with complex karyotype. 9772916 1998