Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
0.600 GeneticVariation disease UNIPROT This meta-analysis showed the evidence that FGFR4 Gly388Arg polymorphism was associated with an increased risk of prostate cancer development and progression, suggesting that FGFR4 Gly388Arg polymorphism could be a marker for prostate cancer development and progression. 21349172 2011
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
0.600 GeneticVariation disease UNIPROT Fibroblast growth factor receptor 4 regulates tumor invasion by coupling fibroblast growth factor signaling to extracellular matrix degradation. 20876804 2010
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
0.600 GeneticVariation disease UNIPROT Our results indicate that the FGFR4 Arg allele of the Gly388Arg polymorphism and the G allele of the rs2011077 polymorphism have a significant impact on the development of prostate cancer and BPH, and the progression of prostate cancer in a Japanese population. 18756523 2008
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
0.600 GeneticVariation disease UNIPROT Our findings indicate that increased receptor stability and sustained FGFR-4 signaling occur in most human prostate cancers due to either the presence of a common genetic polymorphism or the expression of a protein that stabilizes FGFR-4. 18670643 2008
Entrez Id: 2264
Gene Symbol: FGFR4
FGFR4
0.600 Biomarker disease CTD_human Homozygosity for the FGFR-4 Arg388 allele is strongly associated with the occurrence of prostate cancer in white men. 15448004 2004