Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.070 Biomarker phenotype BEFREE Na<sup>+</sup>, K<sup>+</sup>-ATPase inhibition causes hyperactivity and impulsivity in mice via dopamine D2 receptor-mediated mechanism. 30296459 2019
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.070 GeneticVariation phenotype BEFREE Eighty-five patients were assessed overall, and the presence of the T allele (C/T and T/T) of DRD2 c.957C > T polymorphism was found to be significantly associated with the occurrence of defiant and oppositional problems and with attention and hyperactivity problems. 29716536 2018
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.070 GeneticVariation phenotype BEFREE DAT1 intron8 was associated with parent-rated hyperactivity (ηp(2)=.045) and both DAT1 9/10 VNTR (ηp(2)=.105) and DRD2 rs2283265 (ηp(2)=.069) were associated with teacher-rated inattention. 24780147 2014
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.070 Biomarker phenotype BEFREE Furthermore, flies treated with bromocriptine, an agonist of Drosophila dopamine D2 receptor (dD2R), exhibited nocturnal locomotor hyperactivity in a dose-dependent manner and this effect was inhibited in dD2R knockdown flies. 23286280 2013
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.070 AlteredExpression phenotype BEFREE The -141C Del allele, which produces lower expression of DRD2, may protect against dopaminergic hyperactivity in schizophrenia. 18496209 2008
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.070 GeneticVariation phenotype BEFREE For example, the hypoactive alleles of DRD2 and the hyperactive alleles of COMT, which degrade the dopamine in the synaptic cleft, are associated with schizophrenia. 15952869 2005
Entrez Id: 1813
Gene Symbol: DRD2
DRD2
0.070 GeneticVariation phenotype BEFREE The heritability from the DRD2 locus was estimated at 4.27% for hyperactive-impulsive symptoms and 2.12% for inattentive symptoms. 10578241 1999