Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8912
Gene Symbol: CACNA1H
CACNA1H 		0.300 Biomarker phenotype CTD_human Critical role of Cav3.2 T-type calcium channels in the peripheral neuropathy induced by bortezomib, a proteasome-inhibiting chemotherapeutic agent, in mice. 30552955 2019
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1 		0.300 Biomarker phenotype CTD_human Role of CRF1 receptor in post-incisional plasma extravasation and nociceptive responses in mice. 28434951 2017
Entrez Id: 9927
Gene Symbol: MFN2
MFN2 		0.300 Biomarker phenotype CTD_human Involvement of Charcot-Marie-Tooth disease gene mitofusin 2 expression in paclitaxel-induced mechanical allodynia in rats. 28587902 2017
Entrez Id: 5594
Gene Symbol: MAPK1
MAPK1 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 3146
Gene Symbol: HMGB1
HMGB1 		0.300 Biomarker phenotype CTD_human Tissue protein levels were determined by immunoblotting.Repeated i.p. administration of the anti-HMGB1-neutralizing antibody or recombinant human soluble thrombomodulin (rhsTM), known to inactivate HMGB1, prevented the development of hyperalgesia and/or allodynia induced by paclitaxel or vincristine in rats.A single i.p. or intraplantar (i.pl.) administration of the antibody or rhsTM reversed the chemotherapy-induced neuropathy.A single i.pl. administration of a TLR4 antagonist or low molecular weight heparin, known to inhibit RAGE, attenuated the hyperalgesia caused by i.pl. 27474498 2016
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 5595
Gene Symbol: MAPK3
MAPK3 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 5599
Gene Symbol: MAPK8
MAPK8 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 5601
Gene Symbol: MAPK9
MAPK9 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 5590
Gene Symbol: PRKCZ
PRKCZ 		0.300 Biomarker phenotype CTD_human Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain. 27899695 2016
Entrez Id: 2902
Gene Symbol: GRIN1
GRIN1 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.300 Therapeutic phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 1312
Gene Symbol: COMT
COMT 		0.300 Biomarker phenotype CTD_human Generation of membrane-bound catechol-O-methyl transferase deficient mice with disctinct sex dependent behavioral phenotype. 28195063 2016
Entrez Id: 199
Gene Symbol: AIF1
AIF1 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 7056
Gene Symbol: THBD
THBD 		0.300 Therapeutic phenotype CTD_human Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats. 27474498 2016
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 2353
Gene Symbol: FOS
FOS 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 5582
Gene Symbol: PRKCG
PRKCG 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 2670
Gene Symbol: GFAP
GFAP 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.300 Biomarker phenotype CTD_human Citronellol, a natural acyclic monoterpene, attenuates mechanical hyperalgesia response in mice: Evidence of the spinal cord lamina I inhibition. 26141506 2015
Entrez Id: 177
Gene Symbol: AGER
AGER 		0.300 Biomarker phenotype CTD_human Identification of a functional interaction of HMGB1 with Receptor for Advanced Glycation End-products in a model of neuropathic pain. 25014009 2014
Entrez Id: 8989
Gene Symbol: TRPA1
TRPA1 		0.300 Biomarker phenotype CTD_human Antagonism of the transient receptor potential ankyrin 1 (TRPA1) attenuates hyperalgesia and urinary bladder overactivity in cyclophosphamide-induced haemorrhagic cystitis. 23523557 2013
Entrez Id: 11280
Gene Symbol: SCN11A
SCN11A 		0.300 Biomarker phenotype CTD_human Activation of tetrodotoxin-resistant sodium channel NaV1.9 in rat primary sensory neurons contributes to melittin-induced pain behavior. 23264124 2013
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1 		0.300 Biomarker phenotype CTD_human α2δ-1 gene deletion affects somatosensory neuron function and delays mechanical hypersensitivity in response to peripheral nerve damage. 24133248 2013