Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.160 GeneticVariation disease BEFREE To examine the effect of GBA genotype on cognitive progression, patients were classified into those with conversion to mild cognitive impairment or dementia during the study (progression) and those without progression. 27571329 2016
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.160 GeneticVariation disease BEFREE We screened the entire GBA coding region for mutations in controls and in subjects with dementia and LBDNCs and no or low levels of ADNCs (pure dementia with Lewy bodies [pDLB]), LBDNCs and high-level ADNCs (LBD-AD), and high-level ADNCs but without LBDNCs (AD). 23035075 2012
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.160 GeneticVariation disease BEFREE We conducted pooled analyses using logistic regression to investigate GBA1 mutation carrier status as predicting DLB or PD with dementia status, using common control subjects as a reference group. 23588557 2013
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.160 GeneticVariation disease BEFREE In addition, genetic variation in the apolipoprotein E (APOE), catechol-O-methyltransferase (COMT), microtubule-associated protein tau (MAPT), and glucocerebrosidase (GBA) genes may confer risk for cognitive impairment in PD; and gait disturbance may also indicate an increased risk for dementia. 24757111 2014
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.160 GeneticVariation disease BEFREE The development of dementia was influenced by APOE4 allele (HR = 1.90; P = 0.03) and GBA deleterious variants (HR = 2.44; P = 0.01). 28399184 2017
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.160 Biomarker disease BEFREE GBA is a major PD risk factor often associated with dementia. 30245141 2018
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.160 Biomarker disease HPO
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.160 SusceptibilityMutation disease CLINVAR