Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
0.370 Biomarker disease BEFREE These results showed that CCAT2 promoted the radiotherapy resistance of EC cells via negative regulation of the miR‑145/p70S6K1 and the p53 signaling pathways and associated elements may be potential targets for improving the sensitivity of EC radiotherapy. 31789385 2020
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
0.370 GeneticVariation disease BEFREE In addition, the risk-score model -0.0053*log<sub>2</sub>(<i>CADM2</i>)+0.0168*log<sub>2</sub>(<i>SERPINE1</i>)-0.0073*log<sub>2</sub>(ADAMTS9-AS2)+0.0905*log<sub>2</sub>(PVT1)+0.0047*log<sub>2</sub>(hsa-miR372)-0.0193*log<sub>2</sub>(hsa-miR145), (log<sub>2</sub>[gene count]) could improve diagnosis of EC with an AUC of 0.988. 30643460 2019
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
0.370 AlteredExpression disease BEFREE We demonstrated high expression of miR-145 associated with late stage and unfavorable prognosis of esophageal cancer. 29852786 2018
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
0.370 Biomarker disease BEFREE Hence, delivery of PLCE1-targeting miR-145 is a potential therapeutic approach for esophageal cancer. 26657507 2016
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
0.370 AlteredExpression disease BEFREE Compared to the control group, the expression level of miR-145 in the transfected group was significantly higher (185-fold, P < 0.05). miR-145 overexpression significantly inhibited esophageal cancer cell proliferation (P < 0.05). 26156802 2015
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
0.370 Biomarker disease BEFREE Based on our ROC curve analysis data (AUC = 0.74, p < 0.001) miR-145 could be regarded as a potential tumor marker for diagnosis of esophageal cancer. 25773691 2015
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
0.370 GeneticVariation disease BEFREE The combined expression of miR-143 and miR-145 was significantly associated with the risk for esophageal cancer. 22457808 2012
Entrez Id: 406937
Gene Symbol: MIR145
MIR145
0.370 Biomarker disease CTD_human Using 98 formalin-fixed, paraffin-embedded samples obtained from patients with esophageal cancer who had received preoperative chemotherapy followed by surgery, we measured expression levels of several miRNAs that are considered to be involved in the regulation of stem cell function (e.g., let-7a, let-7g, miR-21, miR-134, miR-145, miR-155, miR-200c, miR-203, and miR-296) by real-time reverse transcriptase PCR. 21248297 2011