Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 GeneticVariation disease BEFREE The data point to an important but differential role of the amygdala and dorsal raphe nucleus in 5-HTT genotype-dependent vulnerability to cocaine addiction. 30748070 2020
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 Biomarker disease BEFREE Our studies reveal distinct SERT contributions to cocaine action, reinforcing the possibility of targeting specific aspects of cocaine addiction by modulation of 5-HT signalling. 28585320 2017
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 Biomarker disease PSYGENET We genotyped the SLC6A4 5-HTTLPR (rs4795541, rs25531) and TPH2 1125A>T (rs4290270) variants and evaluated their role in moderating disulfiram treatment for cocaine dependence. 22925276 2012
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 GeneticVariation disease BEFREE We genotyped the SLC6A4 5-HTTLPR (rs4795541, rs25531) and TPH2 1125A>T (rs4290270) variants and evaluated their role in moderating disulfiram treatment for cocaine dependence. 22925276 2012
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 Biomarker disease PSYGENET We investigated the relationship of a polymorphism in the 5' promoter region of the serotonin transporter gene (5-HTTLPR) with prolactin (PRL) response to meta-chlorophenylpiperazine (m-CPP) in a sample of 68 African-American individuals, 35 CD subjects and 33 controls. 17000009 2006
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 Biomarker disease PSYGENET Although platelet 5-HTT densities are reduced in patients with cocaine dependence compared with healthy volunteers, these genotypic variations in the serotonin transporter do not seem to influence levels of platelet 5-HTT in cocaine-dependent patients or healthy volunteers. 15091312 2004
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 Biomarker disease BEFREE Although platelet 5-HTT densities are reduced in patients with cocaine dependence compared with healthy volunteers, these genotypic variations in the serotonin transporter do not seem to influence levels of platelet 5-HTT in cocaine-dependent patients or healthy volunteers. 15091312 2004
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 Biomarker disease PSYGENET Since the serotonin transporter (5HTT) may be involved in modulating effects of cocaine, we investigated whether allelic variants of the 5HTT gene may confer susceptibility to cocaine dependence among African-American individuals. 12218660 2002
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 GeneticVariation disease BEFREE Since the serotonin transporter (5HTT) may be involved in modulating effects of cocaine, we investigated whether allelic variants of the 5HTT gene may confer susceptibility to cocaine dependence among African-American individuals. 12218660 2002
Entrez Id: 6532
Gene Symbol: SLC6A4
SLC6A4
0.550 Biomarker disease CTD_human Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. 11320258 2001