Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.070 GeneticVariation disease BEFREE At 10 % cutoff for CDH1 94% of EOC cases were found to be methylated with mean methylation of 45±13.8, whereas for control mean methylation was found to be 7.3±3.7 amongst 16 % methylation positive control samples. 31653136 2019
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.070 PosttranslationalModification disease BEFREE CDH1, DLEC1 and SFRP5 methylation panel as a prognostic marker for advanced epithelial ovarian cancer. 30324802 2018
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.070 AlteredExpression disease BEFREE Depletion of COX-2, by celecoxib treatment, resulted in attenuated nuclear translocation of Snail, and, in turn, significantly increased E-cadherin in EOC cell line SKOV3, which was established to be due to the reduced binding of Snail onto E-cadherin promoter. 29932878 2018
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.070 GeneticVariation disease BEFREE No significant association was detected between the CDH1 3'-UTR +54C/T polymorphism and survival of the patients with EOC. 27779545 2016
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.070 PosttranslationalModification disease BEFREE Our results suggest that reduced expression of E-cadherin is associated with promoter methylation of E-cadherin gene, in addition to providing evidence for the aberrant nuclear localization of E-cadherin in EOC. 23605324 2013
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.070 GeneticVariation disease BEFREE There was no significant difference in genotype distribution of the -160C/A and -347G/GA SNPs in the E-cadherin gene promoter region between ovarian cancer patients and controls, but haplotype -160A/-347GA relative to haplotype -160C/-347G was 48.6 (95% CI=2.9-806.2) for epithelial ovarian cancer risk. 18035404 2008
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.070 PosttranslationalModification disease BEFREE This study assessed the immuno-expression of E-cadherin and methylation of CDH1 and correlated them with clinical features in primary epithelial ovarian cancer. 16826427 2006