Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.030 GeneticVariation phenotype BEFREE In accordance with previous studies, estrogen receptor mutations were more frequently detected in endocrine-treated MBC patients at progressive disease [34.1% (15/44)] than before the start of endocrine therapy [3.9% (2/51); P = 0.001]. 30296589 2019
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.030 GeneticVariation phenotype BEFREE After adjusting for known risk factors, variants of CYP17A1 (rs6162), HSD17B2 (rs4243229 and rs7201637), and ESR1 (rs1062577) were associated with progressive disease in both cohorts. 23186779 2013
Entrez Id: 2099
Gene Symbol: ESR1
ESR1
0.030 GeneticVariation phenotype BEFREE The study was performed on 112 estrogen receptor-positive primary breast carcinomas from patients with advanced disease and clearly defined types of response (ie, 52 patients with objective response v 60 patients with progressive disease) from start of first-line treatment with tamoxifen. 15681518 2005