Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 AlteredExpression phenotype BEFREE IL-2, IL-4, TNF-α, and IFN-γ levels in peripheral blood were significantly increased among the clinical responders (<i>p</i> < 0.05) while IL-6 and IL-10 were elevated among those with progressive disease (<i>p</i> < 0.05). 31795830 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 Biomarker phenotype BEFREE Other biomarkers (TNF-a and CCL18) could help to identify patients with an enhanced risk of developing pulmonary fibrosis or progressive disease. 30632406 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 Biomarker phenotype BEFREE In Cohort C, the increase in interleukin-8 and tumor necrosis factor-α (TNF-α) was significant in the PD group (p = 0.0063 and p < 0.001, respectively) but not in the SD + PR group (p = 0.67 and p = 0.15, respectively). 30178114 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 Biomarker phenotype BEFREE Using a currently established encephalitic mouse model in which DENV infection causes progressive hunchback posture, limbic seizures, limbic weakness, paralysis, and lethality 7 days postinfection, we showed that TNF-α transgenic mice represented the progressive disease development and administration of neutralizing TNF-α Ab reduced dengue encephalitis and mortality. 30044892 2018
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 Biomarker phenotype BEFREE How TNF regulates disability during progressive disease remains unresolved. 26906225 2016
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 GeneticVariation phenotype BEFREE Furthermore the presence of allele A of the TNF-α -308 polymorphism suggest a risk of the progressive disease. 23395388 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 AlteredExpression phenotype BEFREE Tumour necrosis factor alpha (TNF-alpha) is associated with clinical activity in relapsing-remitting multiple sclerosis (RRMS) and the development of progressive disease. 19201038 2009
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 Biomarker phenotype BEFREE We conclude that a group of B-CLL patients with progressive disease have leukemic B cells able to exert in vitro a TNFalpha-mediated cytotoxicity, which is modulated by cytokines. 15927678 2005
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.090 GeneticVariation phenotype BEFREE The TNF-alpha (-308 bp) promoter/enhancer point mutation and two polymorphisms located within the first intron of the lymphotoxin (LT)-alpha gene showed neither significant allelic deviation for the patient group nor, after analysis of clinical characteristics such as blood counts, stable or progressive disease or response to therapy. 9136953 1997