| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.390 | Biomarker | disease | BEFREE | Pregnancy-associated plasma protein A (PAPP-A) was previously reported to be an inflammatory biomarker and a prognostic marker of acute coronary syndrome (ACS) and involved in the process of atherosclerosis and plaque rupture. | 31582904 | 2019 | ||||
|
0.390 | Biomarker | disease | BEFREE | Relative value of serum pregnancy-associated plasma protein A (PAPP-A) and GRACE score for a 1-year prognostication: A complement to calculation in patients with suspected acute coronary syndrome. | 30058784 | 2018 | ||||
|
0.390 | Biomarker | disease | BEFREE | Pregnancy-associated plasma protein A, myeloperoxidase, and matrix metalloproteinases predict the risk of acute coronary syndrome. | 28491088 | 2017 | ||||
|
0.390 | Biomarker | disease | BEFREE | Pregnancy-associated plasma protein-A is a stronger predictor for adverse cardiovascular outcomes after acute coronary syndrome in type-2 diabetes mellitus. | 28381225 | 2017 | ||||
|
0.390 | AlteredExpression | disease | BEFREE | Positive correlation between pregnancy-associated plasma protein-A level and OX40 ligand expression in patients with acute coronary syndromes. | 21111564 | 2011 | ||||
|
0.390 | AlteredExpression | disease | LHGDN | PAPP-A serum levels increase above normal values within 24 h after onset of symptoms in ACS. | 18855223 | 2009 | ||||
|
0.390 | Biomarker | disease | LHGDN | The highest specificity/sensitivity PAPP-A/proMBP levels for particular acute coronary syndrome (ACS) types were 10.65-14.75 mIU/l. | 17223728 | 2008 | ||||
|
0.390 | Biomarker | disease | LHGDN | PAPP-A and IGF-1 are elevated in patients with acute coronary syndrome. | 18377765 | 2008 | ||||
|
0.390 | Biomarker | disease | BEFREE | Previous studies have shown PAPP-A to be a significant marker of plaque instability and cardiovascular events in patients with acute coronary syndromes. | 17700210 | 2007 | ||||
|
0.390 | Biomarker | disease | CTD_human | PAPP-A is present in unstable plaques, and circulating levels are elevated in acute coronary syndromes; these increased levels may reflect the instability of atherosclerotic plaques. | 11586954 | 2001 |