Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 AlteredExpression disease BEFREE Targeting high-sensitivity C-reactive protein levels in acute coronary syndrome patients undergoing contemporary lipid-lowering therapy: a sub-analysis of the HIJ-PROPER trial. 31699568 2020
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.400 Biomarker disease BEFREE IL-27 is an immunoregulatory cytokine belonging to the IL-6/IL-12 family that was found to be elevated in acute coronary syndrome (ACS) patients. 29428559 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE Optical coherence tomography and C-reactive protein in risk stratification of acute coronary syndromes. 30685100 2019
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE This patient had a clear history of carbon monoxide poisoning, acute respiratory distress, bilateral lung dry and moist rale, chest X-ray showed bilateral pulmonary edema, Electrocardiograph indicated general depression of the ST segment of the leads in the chest, cardiac troponin I (CTNI) increased progressively, cardiac ultrasonography indicated abnormal ventricular wall movement, coronary angiography suggested left main trunk and 3-vessel lesions, suggesting diagnosis acute carbon monoxide poisoning, acute coronary syndrome, acute left heart failure. 30985691 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE Pentraxin-3 vs C-reactive protein and other prognostic biomarkers in acute coronary syndrome: A substudy of the Platelet Inhibition and Patients Outcomes (PLATO) trial. 31017470 2019
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE The aim of this study was to evaluate the impact of implementing a high-sensitivity cardiac troponin I assay with sex-specific diagnostic thresholds for myocardial infarction in women and men with suspected acute coronary syndrome. 31623760 2019
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE Novel high-sensitivity cardiac troponin I assay in patients with suspected acute coronary syndrome. 30442743 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE High sensitivity C-reactive protein to prealbumin ratio measurement as a marker of the prognosis in acute coronary syndrome. 31399624 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE Relationship Between C-Reactive Protein to Albumin Ratio and Thrombus Burden in Patients With Acute Coronary Syndrome. 30808220 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.400 AlteredExpression disease BEFREE This suggests possible prognostic benefits of long-time observation of IL-6 level after the acute coronary syndrome. 31739518 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.400 Biomarker disease BEFREE Admission level of pentraxin 3 is a modestly stronger predictor than high-sensitivity C-reactive protein and interleukin-6, but not than N-terminal prohormone brain natriuretic peptide or high-sensitivity troponin T, concerning cardiovascular outcome in acute coronary syndrome. 31017470 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE Methods and Results We measured baseline serum beta- CT x, NT -pro BNP (N-terminal pro-B-type natriuretic peptide), hsTnT (high-sensitivity cardiac troponin T) and hs CRP (high-sensitivity C-reactive protein) (Roche Diagnostics) in a nested biomarker analysis (n=4094) from a study of patients with non- ST -elevation acute coronary syndrome. 31020897 2019
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.400 Biomarker disease BEFREE VWF, CXCL8 and IL6 might be potential druggable genes for acute coronary syndrome (ACS). 31550669 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 AlteredExpression disease BEFREE The C-reactive protein (CRP) levels obtained at hospital admission are associated with the prognosis of several cardiovascular diseases, including acute coronary syndrome. 31104078 2019
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE Prognostic efficacy of high-sensitivity C-reactive protein to albumin ratio in patients with acute coronary syndrome. 31144514 2019
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE Patients were included if they had cardiac troponin I measured within 24 hours of admission, were older than 18 years of age, and had no evidence of acute coronary syndrome on admission. 29518369 2018
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE The measurement of cardiac troponins, either cardiac troponin I or T, has become the culprit of clinical decision making in patients with suspected acute coronary syndrome (ACS), especially in those with non-ST elevation myocardial infarction (NSTEMI). 30429666 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.400 Biomarker disease BEFREE In this study, we compared the expression levels of the NAMPT/NAD+/Sirt1 signaling pathway as well as NAMPT, CRP and IL-6 in the peripheral blood mononuclear cell (PBMC), and plasma in patients with acute coronary syndromes and healthy subjects, and analyzed their association with macrophage polarization. 30158377 2018
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE High-Sensitivity Cardiac Troponin I and Clinical Risk Scores in Patients With Suspected Acute Coronary Syndrome. 30354460 2018
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE Prognostic implications of detectable cardiac troponin I below the 99th percentile in patients admitted to an emergency department without acute coronary syndrome. 29715175 2018
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE A multi-site coronary sampling study on CRP in non-STEMI: Novel insights into the inflammatory process in acute coronary syndromes. 30268067 2018
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE Cardiac troponin I, measured with a high-sensitivity assay (hs-TnI), is well-established for risk prediction in acute coronary syndromes. 28062625 2017
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.400 Biomarker disease BEFREE In 581 patients undergoing coronary angiography for acute coronary syndrome (ACS) or stable angina pectoris, preprocedural blood samples were drawn for fibrinogen, C-reactive protein (CRP), interleukin-6, and plasminogen activator inhibitor-1 measurements, and virtual histology-intravascular ultrasound of a nonculprit coronary artery was performed. 27755007 2017
Entrez Id: 3569
Gene Symbol: IL6
IL6
0.400 Biomarker disease BEFREE Lutein + zeaxanthin (isomers with lutein being dominant), β-cryptoxanthin, lycopene, α- and β-carotene and IL-6 were measured in plasma from 134 patients with stable angina (SA) and 59 patients with acute coronary syndrome. 28527371 2017
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.400 Biomarker disease BEFREE Patients with suspected acute coronary syndrome (n=1218) underwent high-sensitivity cardiac troponin I measurement at presentation and 3 and 6 or 12 hours. 28034899 2017