Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 331
Gene Symbol: XIAP
XIAP
0.360 Biomarker disease BEFREE Although it has been reported that X-linked inhibitor of apoptosis (XIAP) causes more severe chemoresistance in ovarian cancer cells and is highly expressed in chemoresistant ovarian cancer, the molecular mechanism underlying this dysregulation is unknown. 30639456 2019
Entrez Id: 331
Gene Symbol: XIAP
XIAP
0.360 Biomarker disease BEFREE In summary, our data show that XIAP mediates carboplatin sensitivity of ovarian cancer. 30584333 2018
Entrez Id: 331
Gene Symbol: XIAP
XIAP
0.360 Biomarker disease BEFREE Our data suggest that multiple miRNAs can regulate XIAP via its 3'UTR. miR-137 can sensitise ovarian cancer cells to cisplatin-induced apoptosis, providing new insight into overcoming drug resistance in ovarian cancer. 27875524 2017
Entrez Id: 331
Gene Symbol: XIAP
XIAP
0.360 AlteredExpression disease BEFREE Overexpression of miR-509-3p can not only downregulate the expression of XIAP in ovarian cancer cells but also inhibit the proliferation of EOC cells and increase their sensitivity to cisplatin-induced apoptosis. 26786897 2016
Entrez Id: 331
Gene Symbol: XIAP
XIAP
0.360 Biomarker disease BEFREE This study reveals the potentialities of targeting XIAP in ovarian cancer therapy. 24176845 2013
Entrez Id: 331
Gene Symbol: XIAP
XIAP
0.360 Biomarker disease CTD_human Overexpression of fatty acid synthase in Middle Eastern epithelial ovarian carcinoma activates AKT and Its inhibition potentiates cisplatin-induced apoptosis. 21442130 2011
Entrez Id: 331
Gene Symbol: XIAP
XIAP
0.360 Biomarker disease BEFREE Cisplatin resistance in an ovarian carcinoma is associated with a defect in programmed cell death control through XIAP regulation. 12725530 2003