Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.360 Biomarker disease BEFREE NGS-based methylation profiling differentiates TCF3-HLF and TCF3-PBX1 positive B-cell acute lymphoblastic leukemia. 29334255 2018
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.360 GeneticVariation disease BEFREE Of the 1,129 patients with B-ALL, 64 (5.7%) had t(1;19)/TCF3-PBX1; 51 of whom were treated in the HR arm, but 11 were treated in the VHR and 2 in the SR arm because of physician's preference. 28436581 2017
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.360 Biomarker disease BEFREE Mechanistic investigation led to the identification of Pre-B-cellleukemia transcription factor 3 (PBX3) as a novel and direct downstream target of miR-320a. 27086852 2016
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.360 GeneticVariation disease BEFREE When intensive chemotherapy was used, the TCF3-PBX1 was associated with a favorable outcome in childhood pre-B ALL. 25551271 2015
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.360 GeneticVariation disease BEFREE The 'promiscuous' E2A gene, at 19p13.3, is fused with two different molecular partners, PBX1 and HLF, following two chromosome translocations recurrent in childhood pre-B ALL. 10086727 1999
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.360 GeneticVariation disease BEFREE Thus rearrangement of the E2A gene is not restricted to cases with pre-B ALL but may also occur in acute leukemias with other immunological phenotypes. 1999956 1991
Entrez Id: 6929
Gene Symbol: TCF3
TCF3
0.360 FusionGene disease ORPHANET