Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 960
Gene Symbol: CD44
CD44
0.080 Biomarker disease BEFREE Functional Genomic mRNA Profiling of Colorectal Adenomas: Identification and <i>in vivo</i> Validation of CD44 and Splice Variant CD44v6 as Molecular Imaging Targets. 28255344 2017
Entrez Id: 960
Gene Symbol: CD44
CD44
0.080 GeneticVariation disease BEFREE We therefore analyzed the pattern of CD44 standard and variant (v2-v10) transcripts in colorectal adenomas and carcinomas by exon-specific RT-PCR amplification and sought CD44v transcripts specific for colonic neoplasias. 19787202 2009
Entrez Id: 960
Gene Symbol: CD44
CD44
0.080 PosttranslationalModification disease BEFREE We demonstrated by methylation-sensitive restriction enzyme digestion that the CpG islands of the CD44 promoter were methylated in 6/21 (28%) of benign colorectal adenomas. 12782013 2003
Entrez Id: 960
Gene Symbol: CD44
CD44
0.080 Biomarker disease BEFREE Overexpression of cell surface glycoproteins of the CD44 family is an early event in the colorectal adenoma-carcinoma sequence. 10027409 1999
Entrez Id: 960
Gene Symbol: CD44
CD44
0.080 AlteredExpression disease BEFREE CD44 variant expression was investigated in normal colonic mucosa (n = 36), colorectal adenomas (n = 15), carcinomas (n = 62) and metastases (n = 6) by reverse transcriptase-polymerase chain reaction (RT-PCR) and Southern blotting with exon-specific probes. 9893637 1998
Entrez Id: 960
Gene Symbol: CD44
CD44
0.080 Biomarker disease BEFREE The aim of this study was to analyze the expression of CD44-messenger RNA (mRNA) in colorectal cancer and colorectal adenoma to further elucidate the role of CD44 in colorectal tumorigenesis. 8566581 1996
Entrez Id: 960
Gene Symbol: CD44
CD44
0.080 AlteredExpression disease BEFREE We generated DNA probes for CD44 variable region exons 11 (v6) to 14 (v9) and also for intronic sequences and examined the expression of aberrant CD44 transcripts in digestive tract carcinomas, colorectal adenomas and intestinal metaplasia of the stomach. 8608952 1996
Entrez Id: 960
Gene Symbol: CD44
CD44
0.080 AlteredExpression disease BEFREE CD44 expression in colorectal adenomas is an early event occurring prior to K-ras and p53 gene mutation. 7513984 1994