Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.050 GeneticVariation disease BEFREE Muir-Torre syndrome is defined by the development of sebaceous skin lesions in individuals who carry a germline mismatch repair (MMR) gene mutation. 31162827 2019
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.050 GeneticVariation disease BEFREE Somatic MMR gene mutations as a cause for MSI-H sebaceous neoplasms in Muir-Torre syndrome-like patients. 25504677 2015
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.050 GeneticVariation disease BEFREE The eponymous Muir-Torre syndrome (MTS) is a clinical variant of hereditary non polyposis colorectal cancer, and is defined as an autosomal dominant condition with simultaneous sebaceous neoplasms of the skin and visceral malignant disease resulting from germline mutations in the DNA mismatch repair (MMR) genes. 19449129 2009
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.050 GeneticVariation disease BEFREE Hereditary non-polyposis colorectal cancer (HNPCC), also known as Lynch syndrome types I and II, and the related subtypes Turcot and Muir-Torre syndrome, have all been associated with inheritance of germ line mutations in the DNA mismatch repair (MMR) genes. 17539898 2007
Entrez Id: 4360
Gene Symbol: MRC1
MRC1
0.050 GeneticVariation disease BEFREE Certain MMR gene mutations predispose to combined occurrence of cutaneous sebaceous gland neoplasms and visceral malignancies, which is known as Muir-Torre syndrome (MTS) and regarded as a phenotypic variant of HNPCC. 16327991 2006