Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1482
Gene Symbol: NKX2-5
NKX2-5
0.330 GeneticVariation disease BEFREE In this study, the coding regions and flanking introns of the NKX2-5 gene, which encodes a cardiac transcription factor pivotal for cardiac development and structural remodeling, were sequenced in 210 unrelated patients with sporadic adult-onset DCM. 28690296 2017
Entrez Id: 1482
Gene Symbol: NKX2-5
NKX2-5
0.330 Biomarker disease CTD_human Aryl Hydrocarbon Receptor Ablation in Cardiomyocytes Protects Male Mice From Heart Dysfunction Induced by NKX2.5 Haploinsufficiency. 28973413 2017
Entrez Id: 1482
Gene Symbol: NKX2-5
NKX2-5
0.330 Biomarker disease BEFREE Furthermore, the mutation markedly diminished the synergistic activation of TBX5 with NKX2-5 or GATA4, other two transcription factors causatively linked to DCM. 25725155 2015
Entrez Id: 1482
Gene Symbol: NKX2-5
NKX2-5
0.330 GeneticVariation disease BEFREE In the present study, the whole coding exons and splice junction sites of the NKX2-5 gene, which encodes a homeodomain transcription factor crucial for cardiac development and structural remodeling, were sequenced in 130 unrelated patients with idiopathic DCM. 25503402 2015