Gene: PTEN ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.500 CausalMutation group CLINVAR Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. 10555148 1999
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.500 CausalMutation group CLINVAR Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR. 11504908 2001
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.500 CausalMutation group CLINVAR The PI3K pathway as drug target in human cancer. 20085938 2010
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.500 CausalMutation group CLINVAR Predictive biomarkers of sensitivity to the phosphatidylinositol 3' kinase inhibitor GDC-0941 in breast cancer preclinical models. 20453058 2010
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.500 GeneticVariation group CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016