Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 Biomarker disease BEFREE Analysis of <i>de novo</i> mutations identified <i>GRIN2B</i>, which encodes the GluN2B subunit of NMDA receptors, as a gene linked to ASDs with high probability. 31548203 2019
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 Biomarker disease BEFREE This study supports a possible role of GRIN2B as a candidate gene for the etiology of ASDs. 22326929 2012
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 Biomarker disease CTD_human Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations. 21572417 2011
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 AlteredExpression disease BEFREE Symptomatic mice presenting ASD-like behavior showed decreased levels of GABA pathway proteins such as GAD65/67 and VGAT and altered ratios of the glutamate receptor subunits GluR1/GluR2 in males and NR2A/NR2B in females. 31133774 2019
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 GeneticVariation disease BEFREE Here, we identified two de novo mutations in patients with sporadic SCZ in GRIN2A and one de novo mutation in GRIN2B in a patient with ASD. 22833210 2011
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 Biomarker disease BEFREE The influence of NBEA-KIF21B interactions on GluN2B-NMDAR local recycling may be relevant to mechanisms underlying ASD etiology. 29847800 2018
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 GeneticVariation disease BEFREE A de novo nonsense variant in GRIN2B was identified in an ASD case adding to the growing evidence that this is an important risk gene for the disorder. 24126926 2014
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 GeneticVariation disease BEFREE GRIN2B alterations, including mutation and gene disruption by apparently balanced chromosomal rearrangements, have been described in patients with intellectual disability and autism spectrum disorder. 23918416 2013
Entrez Id: 2904
Gene Symbol: GRIN2B
GRIN2B
0.380 Biomarker disease BEFREE Mutation screening of GRIN2B in schizophrenia and autism spectrum disorder in a Japanese population. 27616045 2016