Gene: RET ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5979
Gene Symbol: RET
RET 		0.740 GeneticVariation disease BEFREE Although it is well known that RET mutation causes multiple endocrine neoplasia type 2A (MEN2A), thus far only 3 individuals have been reported to have MEN2A and renal agenesis/dysgenesis. 24152999 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.740 GeneticVariation disease BEFREE These results suggest that genomic alteration of RET or GDNF is not a major mechanism leading to renal agenesis and other severe kidney development defects. 21490379 2011
Entrez Id: 5979
Gene Symbol: RET
RET 		0.740 GeneticVariation disease BEFREE Mutations in RET were found in 7 of 19 fetuses with bilateral renal agenesis (37%) and 2 of 10 fetuses (20%) with unilateral agenesis. 18252215 2008
Entrez Id: 5979
Gene Symbol: RET
RET 		0.740 Biomarker disease CTD_human Mutations in RET were found in 7 of 19 fetuses with bilateral renal agenesis (37%) and 2 of 10 fetuses (20%) with unilateral agenesis. 18252215 2008
Entrez Id: 5979
Gene Symbol: RET
RET 		0.740 GermlineCausalMutation disease ORPHANET Mutations in RET were found in 7 of 19 fetuses with bilateral renal agenesis (37%) and 2 of 10 fetuses (20%) with unilateral agenesis. 18252215 2008
Entrez Id: 5979
Gene Symbol: RET
RET 		0.740 GeneticVariation disease BEFREE A targeted mutation in the tyrosine kinase domain of RET produced total intestinal aganglionosis and renal agenesis in homozygous transgenic mice. 11316186 2001
Entrez Id: 5979
Gene Symbol: RET
RET 		0.740 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 5979
Gene Symbol: RET
RET 		0.740 Biomarker disease HPO