Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease BEFREE By mining data in the Genotype-Tissue Expression (GTEx) database, we found that CAD-associated risk variants at the JCAD locus are linked to increased JCAD gene expression in human arteries, implicating JCAD as a candidate causal CAD gene. 31539914 2019
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 Biomarker disease BEFREE Identifying this new role for JCAD in atherosclerotic plaque progression highlights the importance of new coronary artery disease genes that mediate blood flow mechanotransduction in the pathogenesis of coronary artery disease. 31584065 2019
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease BEFREE In human tissues, we find that the CAD-associated lead variant, rs2487928, is associated with expression of JCAD in arteries, including atherosclerotic arteries. 29794114 2018
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease GWASCAT Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease. 29212778 2018
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease GWASCAT Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies. 30104761 2018
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease GWASCAT Association analyses based on false discovery rate implicate new loci for coronary artery disease. 28714975 2017
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 Biomarker disease BEFREE Targeted Disruption of JCAD (Junctional Protein Associated With Coronary Artery Disease)/KIAA1462, a Coronary Artery Disease-Associated Gene Product, Inhibits Angiogenic Processes In Vitro and In Vivo. 28705794 2017
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease GWASCAT A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease. 26343387 2015
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease GWASDB Large-scale association analysis identifies new risk loci for coronary artery disease. 23202125 2013
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 Biomarker disease BEFREE KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers. 24349219 2013
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 Biomarker disease CTD_human Replication in an independent sample of 21,408 cases and 19,185 controls identified five loci newly associated with CAD (P < 5 × 10⁻⁸ in the combined discovery and replication analysis): LIPA on 10q23, PDGFD on 11q22, ADAMTS7-MORF4L1 on 15q25, a gene rich locus on 7q22 and KIAA1462 on 10p11. 21378988 2011
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease BEFREE Analysis of a GWA study followed by in silico and wet-lab replication steps identified the KIAA1462 gene, encoding a yet uncharacterized protein, on chromosome 10p11.23 with genome-wide significant association for CAD/MI. 21088011 2011
Entrez Id: 57608
Gene Symbol: JCAD
JCAD
0.470 GeneticVariation disease BEFREE Here, we have identified the protein product for KIAA1462 gene, whose single nucleotide polymorphisms (SNPs) have recently reported to be associated with coronary artery disease, as a novel component of cell-cell junctions. 21884682 2011