Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE Cases with t(9p24;v)/JAK2 are extremely rare; while such cases with a MPN presentation may resemble t(8;9)(p22;p24.1)/PCM1-JAK2, B-ALL cases presenting de novo B-ALL might belong to Ph-like B-ALL. 30401948 2019
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE Integration of ruxolitinib into dose-intensified therapy targeted against a novel JAK2 F694L mutation in B-precursor acute lymphoblastic leukemia. 27860260 2017
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. 26216197 2016
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 AlteredExpression disease BEFREE The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia. 25515960 2015
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 Biomarker disease BEFREE Chromosomal translocations resulting in alternative fusions of the human TEL (ETV6) and JAK2 genes have been observed in cases of acute lymphoblastic leukemia and chronic myelogenous leukemia, but a full understanding of their role in disease etiology has remained elusive. 22733019 2012
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 Biomarker disease BEFREE This case brings the total number of JAK2 rearranged lymphoblastic leukemia cases in the literature to seven. 20594592 2010
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 AlteredExpression disease BEFREE Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. 19965641 2010
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE Moreover, we identified IDH mutations in 2 JAK2 V617F myeloproliferative neoplasias (n = 96), a single case of acute lymphoblastic leukemia (n = 96), and none in chronic myeloid leukemias (n = 81). 20538800 2010
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 Biomarker disease BEFREE CRLF2 and JAK2 in B-progenitor acute lymphoblastic leukemia: a novel association in oncogenesis. 20807819 2010
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia. 18927438 2009
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease LHGDN Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia. 18927438 2009
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE Novel SSBP2-JAK2 fusion gene resulting from a t(5;9)(q14.1;p24.1) in pre-B acute lymphocytic leukemia. 18618714 2008
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE Novel activating JAK2 mutation in a patient with Down syndrome and B-cell precursor acute lymphoblastic leukemia. 17068151 2007
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 Biomarker disease BEFREE In intracellular NOTCH1 (ICN1)- and TEL-JAK2-induced T-cell lymphoblastic leukemia, two mouse models relevant to human malignancies, in vivo inhibition of calcineurin activity by CsA or FK506 induced apoptosis of leukemic cells and rapid tumor clearance, and substantially prolonged mouse survival. 17515895 2007
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE JAK2 mutation was not detected in Ph+ chronic myeloid leukemia (n = 5), acute myeloid leukemia (n = 10), acute lymphoblastic leukemia (n = 10), secondary erythrocytosis (n = 10), or normal bone marrow (n = 10). 16645202 2006
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 GeneticVariation disease BEFREE We show here that a t(9;12)(p24;p13) in a case of early pre-B acute lymphoid leukemia and a t(9;15;12)(p24;q15;p13) in atypical chronic myelogenous leukemia in transformation involve the ETV6 gene at 12p13 and the JAK2 gene at 9p24. 9326218 1997
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.400 CausalMutation disease CGI