Gene: NR1H3 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.360 Biomarker disease BEFREE We evaluated the effects of UA on T0901317 (T090)-induced LXRα activation and steatosis. 30359008 2018
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.360 GeneticVariation disease BEFREE In conclusion, PRMT3 translocation by PA is coupled to the binding of LXRα, which is responsible for the onset of fatty liver. 25187371 2015
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.360 Biomarker disease CTD_human Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction. 23651738 2013
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.360 Biomarker disease BEFREE Liver X receptor α-mediated regulation of lipogenesis by core and NS5A proteins contributes to HCV-induced liver steatosis and HCV replication. 22641099 2012
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.360 AlteredExpression disease BEFREE Our results demonstrate that LQ has an efficacy to activate Nrf2, which contributes to inhibiting the activity of LXRα that leads to SREBP-1c induction and hepatic steatosis. 20677908 2011
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.360 Biomarker disease BEFREE A deficiency of Nrf2 enhanced the ability of LXRα agonist to promote hepatic steatosis, as mediated by lipogenic gene induction. 21504366 2011
Entrez Id: 10062
Gene Symbol: NR1H3
NR1H3 		0.360 AlteredExpression disease BEFREE This study investigated the potential of ILQ for inhibiting liver X receptor-α (LXRα)-mediated lipogenesis and steatosis in hepatocytes and its underlying molecular basis. 20840863 2010