Gene: APC ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Hereditary cancer syndromes in Latino populations: genetic characterization and surveillance guidelines. 28127413 2017
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes. 28944238 2017
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Novel mutations and phenotypic associations identified through APC, MUTYH, NTHL1, POLD1, POLE gene analysis in Indian Familial Adenomatous Polyposis cohort. 28533537 2017
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 Biomarker disease CTD_human Transforming activity and therapeutic targeting of C-terminal-binding protein 2 in Apc-mutated neoplasia. 28414304 2017
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Age- and Gender-Specific Risk of Thyroid Cancer in Patients With Familial Adenomatous Polyposis. 27623068 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Low-level APC mutational mosaicism is the underlying cause in a substantial fraction of unexplained colorectal adenomatous polyposis cases. 26613750 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Clinicopathological features of familial adenomatous polyposis in Korean patients. 27158207 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. 27087319 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes. 26414517 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 GeneticVariation disease CLINVAR Contribution of APC and MUTYH mutations to familial adenomatous polyposis susceptibility in Hungary. 26446593 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR The first European family with gastric adenocarcinoma and proximal polyposis of the stomach: case report and review of the literature. 27343414 2016
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR High-resolution melting (HRM) re-analysis of a polyposis patients cohort reveals previously undetected heterozygous and mosaic APC gene mutations. 25604157 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Next-generation sequencing for genetic testing of familial colorectal cancer syndromes. 26300997 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Attenuated familial adenomatous polyposis with desmoids caused by an APC mutation. 27081525 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Presence of c.3956delC mutation in familial adenomatous polyposis patients from Brazil. 26309368 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Racial variation in frequency and phenotypes of APC and MUTYH mutations in 6,169 individuals undergoing genetic testing. 25590978 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Genetic diagnosis of high-penetrance susceptibility for colorectal cancer (CRC) is achievable for a high proportion of familial CRC by exome sequencing. 25559809 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 GeneticVariation disease CLINVAR Racial variation in frequency and phenotypes of APC and MUTYH mutations in 6,169 individuals undergoing genetic testing. 25590978 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 GeneticVariation disease CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome. 25980754 2015
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Panel-based testing for inherited colorectal cancer: a descriptive study of clinical testing performed by a US laboratory. 24506336 2014
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 CausalMutation disease CLINVAR Attenuated familial adenomatous polyposis manifests as autosomal dominant late-onset colorectal cancer. 24549056 2014
Entrez Id: 324
Gene Symbol: APC
APC 		0.400 GeneticVariation disease CLINVAR The UMD-APC database, a model of nation-wide knowledge base: update with data from 3,581 variations. 24599579 2014