Additionally, systematic review and meta-analysis of the literature for genetic association studies of D2 Thr92Ala polymorphism and DM2 were performed in Medline, Embase, LiLacs, and SciELO, and major meeting databases using the terms 'rs225014' odds ratio (OR) 'thr92ala' OR 'rs225014" genes_norm="1734">T92A' OR 'dio2 a/g'.
This study was designed to test whether homozygosity for the DIO2 A/G polymorphism would be associated with risk of DM2 or elevated levels of diabetes intermediate traits.