Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 Biomarker disease BEFREE Evaluation of ERCC1 expression is not appropriate with a biomarker to detect cases who can benefit from PCT in NPC. 31169219 2019
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 AlteredExpression disease BEFREE The pooled results showed that high/positive expression of ERCC1 predicted poor objective response rate (ORR) [odds ratio (OR) = 2.83; 95% confidence interval (CI) = 2.11-3.80; P <.001], overall survival (OS) [hazard ratio (HR) = 1.77; 95% CI = 1.48-2.12; P <.001], and disease-free survival (DFS) (HR = 1.60; 95% CI = 1.43-1.79; P <.001) in NPC. 31124943 2019
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 AlteredExpression disease BEFREE ERCC1 expression might be a useful predictive marker in patients with locoregionally advanced NPC receiving cisplatin-based concurrent chemoradiotherapy. 29439312 2018
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 AlteredExpression disease BEFREE ERCC1 expression may be a useful predictive marker in patients with locoregionally advanced NPC, who are receiving cisplatin-based CCRT. 29578165 2018
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 Biomarker disease BEFREE Expression of BRCA1 and ERCC1 as predictive clinical outcome after radiochemotherapy in patients with locoregionally moderate-advanced nasopharyngeal carcinoma. 28404895 2017
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 Biomarker disease BEFREE Combined Ki67 and ERCC1 can better predict nasopharyngeal carcinoma prognosis than individual parameters. 29179456 2017
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 AlteredExpression disease BEFREE The expression level of ERCC1 in NPC tissues was detected by immunohistochemistry. 27721259 2016
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 AlteredExpression disease BEFREE The expression of ERCC1 may be a sensitive prognostic indicator of concurrent chemoradiotherapy in locally advanced nasopharyngeal carcinoma. 26125779 2015
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 GeneticVariation disease BEFREE The authors hypothesized that the ERCC1 genotype for the SNPs cytosine-to-thymine substitution at codon 118 (C118T) and cytosine-to-adenine substitution at codon 8092 (C8092A) is prognostic in patients with nasopharyngeal carcinoma (NPC) who receive either radiotherapy (RT) or cisplatin plus RT. 25946469 2015
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 GeneticVariation disease BEFREE The ERCC1 Cys8092Ala polymorphism is an independent predictor of response to radiotherapy for NPC, and the XRCC1 Arg399Glu mutation combined with smoking status seems to predict PFS as well. 25025378 2014
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 GeneticVariation disease BEFREE The ERCC1 C8092A polymorphism might be a useful predictive marker in metastatic/recurrent NPC patients treated with cisplatin-based chemotherapy. 23712330 2013
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 Biomarker disease CTD_human High ERCC1 expression predicts poor locoregional control in NPC. 20605357 2011
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 Biomarker disease BEFREE Pre-treatment tumor biopsy specimens from 41 patients with locally advanced NPC (stage I: 1, II: 10, III: 9, IV: 21 patients) were analyzed for ERCC1 and TS expression by immunohistochemistry. 20153243 2010
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 GeneticVariation disease BEFREE Nasopharyngeal carcinoma (NPC) is a platinum-sensitive cancer and excision repair cross-complementing group 1 (ERCC1) polymorphisms have been shown to predict survival in several cancers following platinum therapy. 19549713 2009
Entrez Id: 2067
Gene Symbol: ERCC1
ERCC1
0.400 GeneticVariation disease BEFREE These results suggested that the polymorphism of ERCC1 8092 C > A might be a contributing factor in the development of NPC in Chinese population. 18615480 2009