Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE High frequency of acquired <i>CSF3R</i> (colony stimulating factor 3 receptor, granulocyte) mutations has been described in patients with severe congenital neutropenia (CN) at pre-leukemia stage and overt acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). 30891028 2019
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE More than 80% of CN patients who develop acute myeloid leukemia or myelodysplastic syndrome reveal CSF3R mutations, suggesting that they are involved in leukemogenesis. 27270496 2016
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE The detection of both RUNX1 and CSF3R mutations could be used as a marker for identifying CN patients with a high risk of progressing to leukemia or MDS. 24523240 2014
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE Truncation mutations of CSF3R, encoding the granulocyte colony-stimulating factor receptor (G-CSFR), are associated with development of myelodysplasia/AML in severe congenital neutropenia. 21911095 2011
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 AlteredExpression group BEFREE The surface expression of G-CSFR on CD(34)(+) cells of MDS-RA and MDS-RAEB patients were 22.788 +/- 14.7628% and 30.682 +/- 15.5346%. 18637807 2009
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE G-CSF receptor (CSF3R) mutations in X-linked neutropenia evolving to acute myeloid leukemia or myelodysplasia. 19794089 2009
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group LHGDN Association with the single-nucleotide polymorphism (Glu785Lys) of the granulocyte colony-stimulating factor receptor with myelodysplastic syndromes and acute myeloid leukemia with multlineage dysplasia. 17024119 2006
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE These results suggest that lifelong altered G-CSF response by the G-CSF-R_785Lys may render individuals susceptible to development of high-risk MDS. 15644419 2005
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 Biomarker group BEFREE This article reviewed the knowledge of the G-CSFR and its role in the disorders of granulopoiesis, including myelodysplastic syndrome (MDS). 15370243 2004
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 AlteredExpression group LHGDN This article reviewed the knowledge of the G-CSFR and its role in the disorders of granulopoiesis, including myelodysplastic syndrome (MDS). 15370243 2004
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE Acquired somatic mutations involving the carboxy-terminus of the G-CSF receptor (G-CSFR) have been found, often in association with myelodysplastic syndrome. 14528102 2003
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE Therefore, we investigated the structural and functional abnormalities of the G-CSFR in 14 patients with MDS and 10 normal subjects. 12012328 2002
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group LHGDN Therefore, we investigated the structural and functional abnormalities of the G-CSFR in 14 patients with MDS and 10 normal subjects. 12012328 2002
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE Absence of mutations in the granulocyte colony-stimulating factor (G-CSF) receptor gene in patients with myelodysplastic syndrome/acute myeloblastic leukaemia occurring after treatment of aplastic anaemia with G-CSF. 11122117 2000
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 GeneticVariation group BEFREE Analysis of the granulocyte colony-stimulating factor receptor gene structure using PCR-SSCP in myeloid leukemia and myelodysplastic syndrome. 9548419 1998
Entrez Id: 1441
Gene Symbol: CSF3R
CSF3R
0.400 CausalMutation group CGI