Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 51119
Gene Symbol: SBDS
SBDS
0.620 Biomarker group GENOMICS_ENGLAND Germline Genetic Predisposition to Hematologic Malignancy. 28297620 2017
Entrez Id: 51119
Gene Symbol: SBDS
SBDS
0.620 Biomarker group BEFREE Our aim was to analyze DICER1 and DROSHA gene and protein expression in mesenchymal stromal cells (the osteoblastic progenitors) obtained from bone marrow of myelodysplastic syndrome patients, in addition to microRNA expression profile and other target genes such as SBDS, a DICER1-related gene that promotes bone marrow dysfunction and myelodysplasia when repressed in a murine model. 22371183 2012
Entrez Id: 51119
Gene Symbol: SBDS
SBDS
0.620 Biomarker group BEFREE We conclude that karyotype instability is part of the natural history of SDS through a specific mutator effect, linked to lacking SBDS protein, with consequent clonal anomalies of chromosomes 7 and 20 in BM, which may eventually promote MDS/AML with the patients' ageing. 19222471 2009
Entrez Id: 51119
Gene Symbol: SBDS
SBDS
0.620 Biomarker group HPO
Entrez Id: 51119
Gene Symbol: SBDS
SBDS
0.620 CausalMutation group CGI